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STT3A, subunit of the oligosaccharyltransferase complex (catalytic)

Summary

Gene Symbol

stt3a

Organism

Xenopus tropicalis (tropical clawed frog)

External Links

NCBI Gene

407861

KEGG Gene ID

xtr:407861

PubChem

407861

Alliance of Genome Resources

Xenbase:XB-GENE-973638

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Magnesium
Manganese
Metal-binding
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6NX25

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein glycosylation	IEA
protein N-linked glycosylation via asparagine	ISS
protein N-linked glycosylation via asparagine	IBA
post-translational protein modification	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

post-translational protein modification

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

post-translational protein modification

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

post-translational protein modification

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

post-translational protein modification

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

post-translational protein modification

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA
endoplasmic reticulum membrane	IEA
oligosaccharyltransferase complex	ISS
membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

oligosaccharyltransferase complex

endoplasmic reticulum protein-containing complex [inference]

oligosaccharyltransferase complex

catalytic complex [inference]

transferase complex [inference]

oligosaccharyltransferase complex

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 6 in total

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2

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GO Term	Evidence Code	PMID
oligosaccharyl transferase activity	IEA
dolichyl-diphosphooligosaccharide-protein glycotransferase activity	ISS
dolichyl-diphosphooligosaccharide-protein glycotransferase activity	IBA
dolichyl-diphosphooligosaccharide-protein glycotransferase activity	IEA
glycosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

hexosyltransferase activity [inference]

oligosaccharyl transferase activity

dolichyl-diphosphooligosaccharide-protein glycotransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dolichyl-diphosphooligosaccharide--protein

Functional Category

O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
dolichyl-diphosphooligosaccharide-protein glycotransferase activity
metal ion binding
oligosaccharyl transferase activity
post-translational protein modification
protein N-linked glycosylation via asparagine
transferase activity

Displaying **all 3** entries
InterPro
Oligosaccharyl transferase STT3, N-terminal domain
Oligosaccharyl transferase, STT3 subunit
STT3/PglB/AglB, core domain

KEGG BRITE Database

Orthology

K07151

Name

dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]

References

12887896

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05976	2.4.99.18	G72079JG	G57930PW

Ortholog

Displaying entries **1 - 10** of 15 in total

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Species	Gene ID	Alliance of Genome Resources
Xenopus laevis	3703	Xenbase:XB-GENE-973644
Danio rerio	16430	ZFIN:ZDB-GENE-021015-3
Danio rerio	33082	ZFIN:ZDB-GENE-021015-3
Saccharomyces cerevisiae S288C	43005	SGD:S000002990
Saccharomyces cerevisiae S288C	68292	SGD:S000002990
Saccharomyces cerevisiae S288C	175886	SGD:S000002990
Saccharomyces cerevisiae S288C	201595	SGD:S000002990
Danio rerio	266797	ZFIN:ZDB-GENE-021015-3
Saccharomyces cerevisiae S288C	323918	SGD:S000002990
Saccharomyces cerevisiae S288C	363160	SGD:S000002990

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Annotation

OrthoDB (Group)

KEGG BRITE Database

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Acknowledgements