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godzilla E3 ubiquitin protein ligase

Summary

Gene Symbol

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

40791

PubChem

40791

Alliance of Genome Resources

FB:FBgn0037442

Annotation

Keyword

Endosome
Glycoprotein
Reference proteome
Signal
Transferase
Transmembrane helix
Ubl conjugation pathway
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9VI20

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
positive regulation of transcytosis	IDA	26974662
endosomal transport	IMP	23353890
ubiquitin-dependent protein catabolic process	IBA
protein ubiquitination	IMP	23353890

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

cellular process [inference]

vesicle-mediated transport [inference]

endosomal transport

cellular localization [inference]

intracellular transport [inference]

endosomal transport

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endosomal transport

intracellular transport [inference]

endosomal transport

establishment of localization in cell [inference]

intracellular transport [inference]

endosomal transport

cellular localization [inference]

intracellular transport [inference]

endosomal transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of transcytosis

regulation of vesicle-mediated transport [inference]

regulation of transcytosis [inference]

positive regulation of transcytosis

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of transcytosis

positive regulation of transport [inference]

positive regulation of transcytosis

positive regulation of multicellular organismal process [inference]

positive regulation of transcytosis

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of transcytosis

regulation of vesicle-mediated transport [inference]

regulation of transcytosis [inference]

positive regulation of transcytosis

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of transcytosis

regulation of transcytosis [inference]

positive regulation of transcytosis

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endosome	IDA	23353890
endosome membrane
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
zinc ion binding	ISM	21912646
ubiquitin protein ligase activity	IBA IDA	23353890 26974662

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity [inference]

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity [inference]

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Zinc finger (C3HC4-type RING finger) family protein

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Zinc finger, RING-type
Zinc finger, RING/FYVE/PHD-type

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
membrane	FB:FBrf0231198
endosome	PMID:23353890

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0112209	developmental and epileptic encephalopathy 73	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 48 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Homo sapiens	11342		HGNC:10057
Mus musculus	24017		MGI:1346341
Homo sapiens	26001		HGNC:24544
Mus musculus	70510		MGI:1917760
Caenorhabditis elegans	181600		WB:WBGene00007666
Rattus norvegicus	360554		RGD:1305972
Xenopus tropicalis	493377		Xenbase:XB-GENE-954771
Rattus norvegicus	681578		RGD:1594062
Danio rerio	793981		ZFIN:ZDB-GENE-040426-772
Drosophila pseudoobscura	4802294	7237_1:0007b6