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Synapsin

Summary

Gene Symbol

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

41247

PubChem

41247

Alliance of Genome Resources

FB:FBgn0004575

Annotation

Keyword

Alternative splicing
Behavior
Direct protein sequencing
Phosphoprotein
Proteomics identification
Reference proteome
Synapse

Proteins

Displaying **all 3** entries
UniProt	Protein Name
E2QCZ0
Q24546
E2QCY9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
male courtship behavior	IMP	15255973
synaptic assembly at neuromuscular junction	IMP	25100589
optomotor response	IMP	15255973
behavioral response to ethanol	IMP	15255973
memory	IMP	15255973

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis

vesicle-mediated transport in synapse [inference]

synaptic vesicle exocytosis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly [inference]

synaptic assembly at neuromuscular junction

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly [inference]

synaptic assembly at neuromuscular junction

synapse organization

synapse assembly [inference]

synaptic assembly at neuromuscular junction

neuromuscular junction development [inference]

synaptic assembly at neuromuscular junction

presynapse organization [inference]

terminal button organization

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis

signal release [inference]

signal release from synapse [inference]

reproductive process [inference]

reproductive behavior [inference]

mating behavior [inference]

courtship behavior [inference]

male courtship behavior

male mating behavior [inference]

male courtship behavior

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning

olfactory learning

memory

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning

olfactory learning

memory

visual behavior [inference]

optokinetic behavior [inference]

optomotor response

chemosensory behavior [inference]

olfactory behavior [inference]

olfactory learning

reproductive behavior [inference]

mating behavior [inference]

courtship behavior [inference]

male courtship behavior

male mating behavior [inference]

male courtship behavior

adult behavior [inference]

behavioral response to ethanol

growth [inference]

developmental growth [inference]

synaptic assembly at neuromuscular junction

response to stimulus [inference]

response to stress [inference]

response to heat

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat

response to radiation [inference]

response to light stimulus [inference]

visual behavior [inference]

optokinetic behavior [inference]

optomotor response

localization [inference]

establishment of localization [inference]

transport [inference]

neurotransmitter transport [inference]

neurotransmitter secretion

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis

vesicle-mediated transport in synapse [inference]

synaptic vesicle exocytosis

secretion [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis

signal release [inference]

signal release from synapse [inference]

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis

signal release [inference]

signal release from synapse [inference]

establishment of localization in cell [inference]

organelle localization [inference]

vesicle localization [inference]

synaptic vesicle localization [inference]

synaptic vesicle clustering

Displaying **all 3** entries
GO Term	Evidence Code	PMID
synaptic vesicle membrane	IBA
terminal bouton	IDA	25100589 8627354
synaptic vesicle	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

presynapse [inference]

terminal bouton

Displaying 1 entry
GO Term	Evidence Code	PMID
ATP binding	IEA

GO Hierarchy

molecular function

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Synapsin

Functional Category

H: Coenzyme transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
ATP binding

Displaying **all 4** entries
InterPro
Pre-ATP-grasp domain superfamily
Synapsin, ATP-binding domain
Synapsin, pre-ATP-grasp domain
Synapsin

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
membrane	FB:FBrf0231198
terminal bouton	PMID:25100589 PMID:8627354

Disease

Disease Ontology

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:0060041	autism spectrum disorder	Alliance of Genome Resources
DOID:0112029	non-syndromic X-linked intellectual disability 50	Alliance of Genome Resources
DOID:0112122	X-linked epilepsy with variable learning disabilities and behavior disorders	Alliance of Genome Resources
DOID:1470	major depressive disorder	Alliance of Genome Resources
DOID:1826	epilepsy	Alliance of Genome Resources
DOID:5419	schizophrenia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 58 in total

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Species	Gene ID	Alliance of Genome Resources
Homo sapiens	6853	HGNC:11494
Homo sapiens	6854	HGNC:11495
Homo sapiens	8224	HGNC:11496
Mus musculus	20964	MGI:98460
Mus musculus	20965	MGI:103020
Rattus norvegicus	24949	RGD:3797
Mus musculus	27204	MGI:1351334
Rattus norvegicus	29130	RGD:3799
Rattus norvegicus	29179	RGD:3798
Caenorhabditis elegans	176987	WB:WBGene00004913

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements