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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

monoamine oxidase A

Summary

Gene Symbol

MAOA

Organism

Homo sapiens (human)

External Links

NCBI Gene

4128

PubChem

4128

Alliance of Genome Resources

HGNC:6833

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Catecholamine metabolism
Direct protein sequencing
Disease variant
FAD
Intellectual disability
Mitochondrion outer membrane
Neurotransmitter degradation
Oxidoreductase
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q53YE7
Q49A63
P21397	Monoamine oxidase type A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
biogenic amine metabolic process	TAS	8211186
positive regulation of signal transduction	IEA
dopamine catabolic process	TAS	24252804

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process

catecholamine metabolic process [inference]

dopamine metabolic process [inference]

dopamine catabolic process

catecholamine catabolic process [inference]

dopamine catabolic process

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process [inference]

dopamine catabolic process

catecholamine catabolic process [inference]

dopamine catabolic process

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process [inference]

dopamine catabolic process

catecholamine catabolic process [inference]

dopamine catabolic process

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process

catecholamine metabolic process [inference]

dopamine metabolic process [inference]

dopamine catabolic process

catecholamine catabolic process [inference]

dopamine catabolic process

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

organic hydroxy compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process [inference]

dopamine catabolic process

catecholamine catabolic process [inference]

dopamine catabolic process

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process [inference]

dopamine catabolic process

catecholamine catabolic process [inference]

dopamine catabolic process

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process [inference]

dopamine catabolic process

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
mitochondrion	IDA
mitochondrion	IBA
mitochondrion	HTP	34800366
mitochondrion	HDA	20833797
mitochondrial outer membrane	TAS	24252804

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	28514442 30021884 33961781
primary amine oxidase activity	IDA	20493079
primary amine oxidase activity	IBA
flavin adenine dinucleotide binding	IBA
aliphatic amine oxidase activity

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the CH-NH2 group of donors [inference]

oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [inference]

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding

ion binding [inference]

anion binding [inference]

flavin adenine dinucleotide binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

oxidase

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying 1 entry
Gene Ontology
oxidoreductase activity

Displaying **all 2** entries
InterPro
Amine oxidase
FAD/NAD(P)-binding domain superfamily

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:0060041	autism spectrum disorder	Alliance of Genome Resources
DOID:0060693	Brunner Syndrome	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:1574	alcohol use disorder	Alliance of Genome Resources
DOID:594	panic disorder	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 26 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	4128	Xenbase:XB-GENE-5749883
Mus musculus	17161		MOUSE66577
Danio rerio	109731	ZFIN:ZDB-GENE-040329-3
Bos taurus	281293		BOVIN37202
Canis lupus familiaris	403450		CANLF19705
Sus scrofa	414424		PIGXX37192
Equus caballus	100033867		HORSE44799
Ornithorhynchus anatinus	100082010		ORNAN09731
Nomascus leucogenys	100589976		NOMLE39319
Monodelphis domestica	100618242		MONDO21963

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.3.0

Last updated: August 4, 2025