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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
steroid sulfatase
Summary
- Gene Symbol
-
- STS
- Aliases
-
- ARSC
- arylsulfatase C
- steryl-sulfatase
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cytoplasmic vesicle
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Hydrolase
- Ichthyosis
- Metal-binding
- Pregnancy
- Proteomics identification
- Reference proteome
- Signal
- Steroid metabolism
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A6PYA4 |
|
| P08842 |
|
| A0A590UJL0 |
|
| Q0W975 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| steroid catabolic process |
|
|
| epidermis development |
|
|
| female pregnancy |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum lumen |
|
|
| intracellular membrane-bounded organelle |
|
|
| endosome |
|
|
| endoplasmic reticulum |
|
|
| endoplasmic reticulum membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| steryl-sulfatase activity | ||
| sulfuric ester hydrolase activity | ||
| metal ion binding | ||
| arylsulfatase activity |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060582 | Noonan syndrome 4 | |
| DOID:0060583 | Noonan syndrome 5 | |
| DOID:0060584 | Noonan syndrome 6 | |
| DOID:0060585 | Noonan syndrome 7 | |
| DOID:0060586 | Noonan syndrome 8 | |
| DOID:0060587 | Noonan syndrome 9 | |
| DOID:0060588 | Noonan syndrome 10 | |
| DOID:0060608 | microcephalic osteodysplastic primordial dwarfism type I | |
| DOID:0060609 | microcephalic osteodysplastic primordial dwarfism type II | |
| DOID:0060642 | recessive dystrophic epidermolysis bullosa |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000028 | Cryptorchidism |
| HP:0000083 | Renal insufficiency |
| HP:0000122 | Unilateral renal agenesis |
| HP:0000135 | Hypogonadism |
| HP:0000717 | Autism |
| HP:0000958 | Dry skin |
| HP:0000962 | Hyperkeratosis |
| HP:0000966 | Hypohidrosis |
| HP:0000982 | Palmoplantar keratoderma |
| HP:0001249 | Intellectual disability |
| Disease ID | Disease Name |
|---|---|
| ORPHA:461 |
|
| OMIM:308100 |
|
| ORPHA:281090 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP006680
- Gene Name
- steroid sulfatase (microsomal), isozyme S
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 179194 | WB:WBGene00006309 | ||
| 103189013 | CALMI40455 | ||
| 402795 | ZFIN:ZDB-GENE-030717-5 | DANRE16756 | |
| 108259020 | ICTPU21356 | ||
| 105022503 | ESOLU64546 | ||
| 115179180 | SALTR06410 | ||
| 103477228 | POERE21777 | ||
| 115576556 | SPAAU66468 | ||
| 108709162 | Xenbase:XB-GENE-17345455 | ||
| 100495327 | Xenbase:XB-GENE-1013410 |
