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methionyl-tRNA synthetase 1

Summary

Gene Symbol

MARS1

Organism

Homo sapiens (human)

External Links

NCBI Gene

4141

PubChem

4141

Alliance of Genome Resources

HGNC:6898

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Aminoacyl-tRNA synthetase
Charcot-Marie-Tooth disease
Cytoplasm
Disease variant
Hereditary spastic paraplegia
Nucleus
Phosphoprotein
Protein biosynthesis
Reference proteome
tRNA-binding

Proteins

Displaying 1 entry
UniProt	Protein Name
P56192	Methionyl-tRNA synthetase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

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GO Term	Evidence Code	PMID
tRNA aminoacylation for protein translation	TAS
methionyl-tRNA aminoacylation	IDA	11714285
methionyl-tRNA aminoacylation	IMP	33909043
methionyl-tRNA aminoacylation	IBA
rRNA transcription	IMP	10791971

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

response to platelet-derived growth factor [inference]

cellular response to platelet-derived growth factor stimulus

response to epidermal growth factor [inference]

cellular response to epidermal growth factor stimulus

cellular response to growth factor stimulus [inference]

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
nucleolus	IDA	10791971
cytoplasm	IDA	10791971 22424946
cytosol	TAS
cytosol	IDA	19289464
cytosol	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

aminoacyl-tRNA synthetase multienzyme complex

catalytic complex [inference]

aminoacyl-tRNA synthetase multienzyme complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
tRNA binding	IEA
methionine-tRNA ligase activity	TAS
methionine-tRNA ligase activity	IDA	11714285
methionine-tRNA ligase activity	IBA
ATP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

ligase activity [inference]

ligase activity, forming carbon-oxygen bonds [inference]

aminoacyl-tRNA ligase activity [inference]

methionine-tRNA ligase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

catalytic activity, acting on a tRNA [inference]

aminoacyl-tRNA ligase activity [inference]

methionine-tRNA ligase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

tRNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

METHIONINE--TRNA LIGASE

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
V: Defense mechanisms

Displaying **all 6** entries
Gene Ontology
ATP binding
ligase activity
methionine-tRNA ligase activity
methionyl-tRNA aminoacylation
nucleotide binding
tRNA aminoacylation for protein translation

Displaying **all 9** entries
InterPro
Aminoacyl-tRNA synthetase, class I, conserved site
Aminoacyl-tRNA synthetase, class Ia, anticodon-binding
Methionine-tRNA ligase, type 1
Methioninyl-tRNA synthetase core domain
Methionyl-tRNA synthetase, Zn-domain
Methionyl-tRNA synthetase, anticodon-binding domain
Methionyl-tRNA synthetase
Methionyl/Leucyl tRNA synthetase
Rossmann-like alpha/beta/alpha sandwich fold

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0070454	hereditary spastic paraplegia 70	Alliance of Genome Resources
DOID:0110173	Charcot-Marie-Tooth disease axonal type 2U	Alliance of Genome Resources
DOID:0111866	trichothiodystrophy	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 73 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	4141	Xenbase:XB-GENE-5952509
Mus musculus	216443		MOUSE00860
Rattus norvegicus	299851		RATNO39080
Danio rerio	338183		DANRE38639
Pan troglodytes	452016		PANTR05485
Canis lupus familiaris	474414		CANLF01346
Bos taurus	512531		BOVIN29567
Macaca mulatta	714744		MACMU05455
Equus caballus	100053373		HORSE36344
Ornithorhynchus anatinus	100084729		ORNAN00707

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements