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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
carbohydrate sulfotransferase 6
Summary
- Gene Symbol
-
- CHST6
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Carbohydrate metabolism
- Corneal dystrophy
- Disease variant
- Glycoprotein
- Golgi apparatus
- Reference proteome
- Signal-anchor
- Transferase
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9GZX3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| N-acetylglucosamine metabolic process | ||
| keratan sulfate biosynthetic process | ||
| sulfur compound metabolic process | ||
| carbohydrate metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi apparatus | ||
| trans-Golgi network | ||
| Golgi membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| N-acetylglucosamine 6-O-sulfotransferase activity | ||
| keratan sulfotransferase activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- sulfotransferase
- Functional Category
-
- G: Carbohydrate transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| N-acetylglucosamine 6-O-sulfotransferase activity |
| N-acetylglucosamine metabolic process |
| sulfotransferase activity |
| transferase activity |
| InterPro |
|---|
| Carbohydrate sulfotransferase |
| P-loop containing nucleoside triphosphate hydrolase |
| Sulfotransferase domain |
GlycoGene Database (GGDB)
- GGDB ID
- gg030
- Gene Symbol
-
- CHST6
- Orthologous Gene
| Species | Protein | mRNA |
|---|---|---|
| Rattus norvegicus | XP_226482 | XM_226482 |
| Mus musculus | NP_064334 | NM_019950 |
KEGG BRITE Database
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2565 | macular corneal dystrophy |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000484 | Hyperopic astigmatism |
| HP:0000495 | Recurrent corneal erosions |
| HP:0000531 | Corneal crystals |
| HP:0000613 | Photophobia |
| HP:0001131 | Corneal dystrophy |
| HP:0001141 | Severely reduced visual acuity |
| HP:0001939 | Abnormality of metabolism/homeostasis |
| HP:0003621 | Juvenile onset |
| HP:0007754 | Macular dystrophy |
| Disease ID | Disease Name |
|---|---|
| OMIM:217800 |
|
| ORPHA:98969 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 33913 | FB:FBgn0031826 | |||
| 33914 | FB:FBgn0051637 | |||
| 56773 | MGI:1931825 | MOUSE58499 | ||
| 307859 | RGD:1561144 | RATNO14403 | ||
| 444431 | Xenbase:XB-GENE-960886 | |||
| 489707 | CANLF15944 | |||
| 538464 | BOVIN10159 | |||
| 711570 | MACMU26190 | |||
| 100029207 | MONDO02937 | |||
| 100068994 | HORSE31535 |
