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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
carbohydrate sulfotransferase 6
Summary
- Gene Symbol
-
- CHST6
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Carbohydrate metabolism
- Corneal dystrophy
- Disease variant
- Glycoprotein
- Golgi apparatus
- Reference proteome
- Signal-anchor
- Transferase
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9GZX3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| N-acetylglucosamine metabolic process | ||
| keratan sulfate biosynthetic process | ||
| sulfur compound metabolic process | ||
| carbohydrate metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi apparatus | ||
| trans-Golgi network | ||
| Golgi membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| N-acetylglucosamine 6-O-sulfotransferase activity | ||
| keratan sulfotransferase activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- sulfotransferase
- Functional Category
-
- G: Carbohydrate transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| N-acetylglucosamine 6-O-sulfotransferase activity |
| N-acetylglucosamine metabolic process |
| sulfotransferase activity |
| transferase activity |
| InterPro |
|---|
| Carbohydrate sulfotransferase |
| P-loop containing nucleoside triphosphate hydrolase |
| Sulfotransferase domain |
GlycoGene Database (GGDB)
- GGDB ID
- gg030
- Gene Symbol
-
- CHST6
- Orthologous Gene
| Species | Protein | mRNA |
|---|---|---|
| Rattus norvegicus | XP_226482 | XM_226482 |
| Mus musculus | NP_064334 | NM_019950 |
KEGG BRITE Database
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2565 | macular corneal dystrophy |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0007759 | Opacification of the corneal stroma |
| HP:0007856 | Punctate opacification of the cornea |
| HP:0012155 | Decreased corneal sensation |
| HP:0100689 | Decreased corneal thickness |
| HP:0200026 | Ocular pain |
| Disease ID | Disease Name |
|---|---|
| OMIM:217800 |
|
| ORPHA:98969 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100086595 | ORNAN03122 | |||
| 100170782 | ZFIN:ZDB-GENE-060810-74 | DANRE26836 | ||
| 100403035 | CALJA21950 | |||
| 100437082 | 9601_0:003ee1 | PONAB10924 | ||
| 100477677 | AILME04069 | |||
| 100495636 | Xenbase:XB-GENE-960885 | |||
| 100496630 | Xenbase:XB-GENE-5812130 | |||
| 100522551 | PIGXX27062 | |||
| 100549737 | MELGA03662 | |||
| 100604854 | NOMLE24259 |
