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imidazole glycerol phosphate synthase subunit HisF

Summary

Gene Symbol

hisF

Organism

Pyrococcus furiosus DSM 3638

External Links

NCBI Gene: 41713491
PubChem: 41713491

Annotation

Keyword

Cytoplasm
Histidine biosynthesis
Lyase
Reference proteome

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P58800	IGP synthase cyclase subunit IGP synthase subunit HisF ImGP synthase subunit HisF
I6U9Y7	IGP synthase cyclase subunit IGP synthase subunit HisF ImGP synthase subunit HisF
A0A5C0XTT5	IGP synthase cyclase subunit IGP synthase subunit HisF ImGP synthase subunit HisF

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
histidine biosynthetic process

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

histidine metabolic process [inference]

histidine biosynthetic process

amino acid biosynthetic process [inference]

histidine biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

histidine metabolic process [inference]

histidine biosynthetic process

amino acid biosynthetic process [inference]

histidine biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

primary metabolic process [inference]

amino acid metabolic process [inference]

histidine metabolic process [inference]

histidine biosynthetic process

amino acid biosynthetic process [inference]

histidine biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

histidine metabolic process [inference]

histidine biosynthetic process

amino acid biosynthetic process [inference]

histidine biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

histidine metabolic process [inference]

histidine biosynthetic process

amino acid biosynthetic process [inference]

histidine biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

histidine metabolic process [inference]

histidine biosynthetic process

amino acid biosynthetic process [inference]

histidine biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

histidine metabolic process [inference]

histidine biosynthetic process

amino acid biosynthetic process [inference]

histidine biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

histidine biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying **all 2** entries
GO Term	Evidence Code	PMID
lyase activity
imidazoleglycerol-phosphate synthase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

pentosyltransferase activity [inference]

imidazoleglycerol-phosphate synthase activity

lyase activity

Gene Ontology information from NCBI Gene and UniProt.

Rhea

L-glutamine + 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-β-D-ribosyl)imidazole-4-carboxamide

H⁺ + L-glutamate + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 5-amino-1-(5-phospho-β-D-ribosyl)imidazole-4-carboxamide

Enzyme

4.3.2.10

PMID

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024