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neural EGFL like 2

Summary

Gene Symbol

NELL2

Organism

Gallus gallus (chicken)

External Links

NCBI Gene: 417799
PubChem: 417799

Annotation

Keyword

Calcium
Disulfide bond
EGF-like domain
Glycoprotein
Reference proteome
Repeat
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q90827	93 kDa protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
positive regulation of cell division
cell population proliferation
commissural neuron axon guidance
positive regulation of neuron differentiation
negative regulation of retinal ganglion cell axon guidance

GO Hierarchy

biological process

cellular process [inference]

cell population proliferation

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

mesenchymal cell migration [inference]

neural crest cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance [inference]

commissural neuron axon guidance

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of chemotaxis [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of chemotaxis [inference]

negative regulation of chemotaxis [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of axon guidance [inference]

regulation of retinal ganglion cell axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of cell division

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

negative regulation of biological process [inference]

negative regulation of locomotion [inference]

negative regulation of chemotaxis [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of chemotaxis [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of chemotaxis [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of chemotaxis [inference]

negative regulation of chemotaxis [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of axon guidance [inference]

regulation of retinal ganglion cell axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of chemotaxis [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of cellular process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of cell division

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of axon guidance [inference]

regulation of retinal ganglion cell axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of cell division [inference]

positive regulation of cell division

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular space
cytoplasm

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IEA	22301074
heparin binding
identical protein binding
calcium ion binding	IEA	22301074
protein kinase C binding

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein kinase C binding

identical protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Protein kinase C-binding protein

Functional Category

G: Carbohydrate transport and metabolism
I: Lipid transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 2** entries
Gene Ontology
calcium ion binding
heparin binding

Displaying **all 7** entries
InterPro
EGF domain
EGF-like calcium-binding domain
EGF-like calcium-binding, conserved site
EGF-like domain
EGF-type aspartate/asparagine hydroxylation site
NOTCH1 EGF-like calcium-binding domain
VWFC domain

Ortholog

Displaying entries **1 - 10** of 28 in total

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Species	Gene ID	OrthoDB
Meleagris gallopavo	100539582	9103_1:000138
Meleagris gallopavo	100549928	9103_0:001869
Anas platyrhynchos	101791606	8839_0:00176a
Anas platyrhynchos	101793748	8839_0:00082f
Anser cygnoides	106033882	8845_0:0031a2
Anser cygnoides	106047533	8845_0:0012cd
Coturnix japonica	107309796	93934_0:000208
Coturnix japonica	107314305	93934_0:00173c
Numida meleagris	110392690	8996_0:0002a3
Numida meleagris	110401221	8996_0:001d75