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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
meprin A subunit alpha
Summary
- Gene Symbol
-
- MEP1A
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Disulfide bond
- EGF-like domain
- Metal-binding
- Metalloprotease
- Proteoglycan
- Proteomics identification
- Reference proteome
- Signal
- Transmembrane helix
- Zinc
- Zymogen
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis |
|
|
| signaling receptor ligand precursor processing | ||
| epidermal growth factor receptor ligand maturation |
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane |
|
|
| plasma membrane | ||
| meprin A complex | ||
| extracellular space | ||
| extracellular exosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| zinc ion binding | ||
| metallodipeptidase activity | ||
| metalloendopeptidase activity | ||
| metallopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- metalloendopeptidase
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| zinc ion binding |
| InterPro |
|---|
| Metallopeptidase, catalytic domain superfamily |
| Peptidase M12A |
| Peptidase, metallopeptidase |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10283 | prostate cancer |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 462745 | 9598_0:001dd8 | PANTR38316 | ||
| 481826 | CANLF02818 | |||
| 548484 | Xenbase:XB-GENE-921661 | |||
| 553530 | ZFIN:ZDB-GENE-041001-209 | |||
| 565535 | ZFIN:ZDB-GENE-041001-208 | |||
| 704781 | MACMU33946 | |||
| 100037179 | Xenbase:XB-GENE-921672 | |||
| 100068383 | HORSE19509 | |||
| 100080933 | ORNAN27472 | |||
| 100154136 | PIGXX31689 |
