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alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase

Summary

Gene Symbol

MGAT5

Aliases

GNT-V
MGAT5A
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

Organism

Homo sapiens (human)

External Links

NCBI Gene

4249

GGDB ID

gg130

HGNC

7049

mRNA

NM_002410

map

2q21

Protein

NP_002401

OMIM

601774

KEGG Gene ID

hsa:4249

PubChem

4249

Alliance of Genome Resources

HGNC:7049

Annotation

Keyword

3D-structure
Direct protein sequencing
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Secreted
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q09328	Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase V GlcNAc-T V Mannoside acetylglucosaminyltransferase 5 N-acetylglucosaminyl-transferase V

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
protein N-linked glycosylation via asparagine	IDA	10395745 30140003
protein N-linked glycosylation	IBA IDA	24846175
positive regulation of cell migration	IDA	24846175
viral protein processing	TAS
negative regulation of protein tyrosine phosphatase activity

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

viral process [inference]

viral protein processing

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of phosphatase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of phosphatase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of cell motility [inference]

positive regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of hydrolase activity [inference]

regulation of phosphatase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane	IDA	10395745
Golgi apparatus	IBA
Golgi membrane	ISS TAS
extracellular exosome	HDA	23533145

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

Golgi apparatus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein phosphatase inhibitor activity	IDA	24846175
manganese ion binding	IDA	10395745
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	IBA IDA NAS TAS	10395745 24846175 30140003 8292036