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Malvolio

Summary

Gene Symbol

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

42490

PubChem

42490

Alliance of Genome Resources

FB:FBgn0011672

Annotation

Keyword

Alternative splicing
Glycoprotein
Proteomics identification
Reference proteome
Transmembrane helix
Transport

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A0A0B4KGL5
A4V370
P49283
A0A0B4K7L4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
viral entry into host cell	IMP	21843867
transition metal ion transport	IMP	9390942
sensory perception of sweet taste	IMP	7621816 9390942
iron ion transmembrane transport	IBA IMP	21346125
copper ion import	IMP	18281333

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

iron ion transmembrane transport

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of taste [inference]

sensory perception of sweet taste

homeostatic process [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

copper ion homeostasis

inorganic ion homeostasis [inference]

copper ion homeostasis

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport

transition metal ion transport

copper ion transport [inference]

copper ion import

iron ion transport [inference]

iron ion transmembrane transport

manganese ion transport

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

iron ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

regulation of monoatomic cation transmembrane transport [inference]

regulation of iron ion transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of iron ion transport [inference]

positive regulation of iron ion transport [inference]

positive regulation of iron ion transmembrane transport

regulation of iron ion transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

regulation of monoatomic cation transmembrane transport [inference]

regulation of iron ion transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

positive regulation of monoatomic ion transport [inference]

positive regulation of iron ion transport [inference]

positive regulation of iron ion transmembrane transport

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

positive regulation of monoatomic ion transport [inference]

positive regulation of iron ion transport [inference]

positive regulation of iron ion transmembrane transport

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

positive regulation of monoatomic ion transport [inference]

positive regulation of iron ion transport [inference]

positive regulation of iron ion transmembrane transport

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

regulation of monoatomic cation transmembrane transport [inference]

regulation of iron ion transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of iron ion transmembrane transport

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA IDA ISM	18281333 7621816
endosome	IDA	18281333
endosome membrane	IBA
membrane	IDA IEA	17932044

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
metal ion transmembrane transporter activity	IEA
copper ion transmembrane transporter activity	IMP	18281333
symporter activity	IGI	17932044
iron ion transmembrane transporter activity	IBA IMP	9390942
cadmium ion transmembrane transporter activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity

transition metal ion transmembrane transporter activity [inference]

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity

transition metal ion transmembrane transporter activity [inference]

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
endosome	PMID:18281333
plasma membrane	PMID:18281333
membrane	FB:FBrf0231198 PMID:17932044

Disease

Disease Ontology

Displaying entries **1 - 10** of 29 in total

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DO ID	Disease Name	Source
DOID:0050425	restless legs syndrome	Alliance of Genome Resources
DOID:0050456	Buruli ulcer disease	Alliance of Genome Resources
DOID:0050589	inflammatory bowel disease	Alliance of Genome Resources
DOID:0060704	lymphoproliferative syndrome	Alliance of Genome Resources
DOID:0080855	Parkinsonism	Alliance of Genome Resources
DOID:1024	leprosy	Alliance of Genome Resources
DOID:11054	urinary bladder cancer	Alliance of Genome Resources
DOID:11335	sarcoidosis	Alliance of Genome Resources
DOID:11758	iron deficiency anemia	Alliance of Genome Resources
DOID:11759	hypochromic anemia	Alliance of Genome Resources