GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

HMG Coenzyme A reductase

Summary

Gene Symbol

Hmgcr

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

42803

PubChem

42803

Alliance of Genome Resources

FB:FBgn0263782

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
Isoprene biosynthesis
NADP
Oxidoreductase
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P14773

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of 15 in total

« First

‹ Prev

1

2

3
GO Term	Evidence Code	PMID
ecdysis, chitin-based cuticle	IMP	19595690
embryonic heart tube development	IMP	16857902
germ cell attraction	TAS	12814944 15196560 9637912
germ cell attraction	IDA	19389345
positive regulation of Ras protein signal transduction	HGI	24643257

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

isoprenoid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

sterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

sterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

sterol biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

isoprenoid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound metabolic process [inference]

sterol metabolic process [inference]

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

cellular process [inference]

cellular process involved in reproduction in multicellular organism [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

coenzyme A metabolic process

purine nucleoside bisphosphate metabolic process [inference]

coenzyme A metabolic process

cell motility [inference]

cell migration [inference]

germ cell migration

cell chemotaxis [inference]

germ cell attraction

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development

cellular process involved in reproduction in multicellular organism [inference]

multicellular organismal process [inference]

behavior [inference]

locomotory behavior

molting cycle process [inference]

ecdysis, chitin-based cuticle

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

embryonic heart tube development

tube development [inference]

embryonic heart tube development

animal organ development [inference]

gonad development

reproductive structure development [inference]

gonad development

locomotion [inference]

taxis [inference]

chemotaxis [inference]

positive chemotaxis [inference]

germ cell attraction

cell chemotaxis [inference]

germ cell attraction

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

Displaying **all 4** entries
GO Term	Evidence Code	PMID
peroxisomal membrane	ISS	22758915
peroxisomal membrane	IBA
endoplasmic reticulum membrane	IBA
endoplasmic reticulum membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

microbody membrane [inference]

peroxisomal membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

microbody membrane [inference]

peroxisomal membrane

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

microbody membrane [inference]

peroxisomal membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
hydroxymethylglutaryl-CoA reductase (NADPH) activity	IBA
hydroxymethylglutaryl-CoA reductase (NADPH) activity	IEA
NADP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

hydroxymethylglutaryl-CoA reductase (NADPH) activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
membrane	FB:FBrf0231198

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:423	myopathy	Alliance of Genome Resources

About Release Notes Help Feedback

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026