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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
matrix metallopeptidase 1
Summary
- Gene Symbol
-
- MMP1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Autocatalytic cleavage
- Calcium
- Collagen
- Collagen degradation
- Direct protein sequencing
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Host-virus interaction
- Metal-binding
- Metalloprotease
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| cellular response to UV-A | ||
| positive regulation of protein-containing complex assembly | ||
| extracellular matrix disassembly | ||
| collagen catabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix | ||
| extracellular region | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| zinc ion binding | ||
| metalloendopeptidase activity | ||
| endopeptidase activity | ||
| peptidase activity | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- metallopeptidase
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| collagen catabolic process |
| extracellular matrix organization |
| hydrolase activity |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| zinc ion binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:0050851 | glomerulosclerosis | |
| DOID:0050855 | renal fibrosis | |
| DOID:0060224 | atrial fibrillation | |
| DOID:0060249 | scoliosis | |
| DOID:0060903 | thrombosis | |
| DOID:0080600 | COVID-19 | |
| DOID:0080933 | immunoglobulin light chain amyloidosis | |
| DOID:1070 | primary open angle glaucoma | |
| DOID:10763 | hypertension |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 83995 | MGI:1933846 | MOUSE64397 | ||
| 83996 | MGI:1933847 | MOUSE64514 | ||
| 178748 | WB:WBGene00016283 | |||
| 281308 | BOVIN06331 | |||
| 300338 | RGD:1306843 | RATNO40453 | ||
| 300339 | RGD:1307917 | RATNO40388 | ||
| 451510 | 9598_0:0033ac | PANTR04182 | ||
| 495287 | Xenbase:XB-GENE-856365 | |||
| 594916 | Xenbase:XB-GENE-485009 | |||
| 703653 | MACMU10439 |
