matrix metallopeptidase 3
| UniProt | Protein Name |
|---|---|
| P08254 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| extracellular matrix disassembly | ||
| protein catabolic process | ||
| extracellular matrix organization | ||
| regulation of cell migration |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| nucleus | ||
| mitochondrion | ||
| cytosol |
| GO Term | Evidence Code | PMID |
|---|---|---|
| endopeptidase activity | ||
| metalloendopeptidase activity | ||
| metalloendopeptidase activity | ||
| serine-type endopeptidase activity | ||
| protein binding |
| Gene Ontology |
|---|
| collagen catabolic process |
| extracellular matrix organization |
| hydrolase activity |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| zinc ion binding |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060224 | atrial fibrillation | |
| DOID:0060903 | thrombosis | |
| DOID:13001 | carotid stenosis | |
| DOID:14175 | von Hippel-Lindau disease | |
| DOID:1612 | breast cancer | |
| DOID:2349 | arteriosclerosis | |
| DOID:3393 | coronary artery disease | |
| DOID:418 | systemic scleroderma | |
| DOID:4450 | renal cell carcinoma | |
| DOID:4914 | esophagus adenocarcinoma |
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 4312 | WB:WBGene00016283 | ||
| 4314 | Xenbase:XB-GENE-5932566 | ||
| 4317 | WB:WBGene00016283 | ||
| 4321 | WB:WBGene00016283 | ||
| 4322 | WB:WBGene00016283 | ||
| 4323 | WB:WBGene00010423 | ||
| 4324 | WB:WBGene00010423 | ||
| 4325 | WB:WBGene00010423 | ||
| 4326 | WB:WBGene00010423 | ||
| 4327 | WB:WBGene00016283 |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025