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fucosyltransferase 8

Summary

Gene Symbol

Fut8

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

432392

KEGG Gene ID

rno:432392

PubChem

432392

Alliance of Genome Resources

RGD:1303096

Annotation

Keyword

Coiled coil
Disulfide bond
Glycosyltransferase
Golgi apparatus
Phosphoprotein
Reference proteome
SH3 domain
SH3-binding
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q6EV76	GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase GDP-fucose--glycoprotein fucosyltransferase Glycoprotein 6-alpha-L-fucosyltransferase
D4IGX4	GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase GDP-fucose--glycoprotein fucosyltransferase Glycoprotein 6-alpha-L-fucosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of 28 in total

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GO Term	Evidence Code	PMID
regulation of gene expression	ISO
regulation of gene expression	IEA
fibroblast migration	ISO
fibroblast migration	IEA
cell migration	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

phosphorus metabolic process [inference]

GDP-L-fucose metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

glycosylation [inference]

fucosylation [inference]

N-glycan fucosylation

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

receptor metabolic process

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

integrin-mediated signaling pathway

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

phosphorus metabolic process [inference]

GDP-L-fucose metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

cell motility [inference]

cell migration

ameboidal-type cell migration [inference]

fibroblast migration

multicellular organismal process [inference]

respiratory gaseous exchange by respiratory system

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of response to stimulus [inference]

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of cellular response to oxidative stress

regulation of response to oxidative stress [inference]

regulation of cellular response to oxidative stress

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

integrin-mediated signaling pathway

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular response to stress [inference]

regulation of cellular response to oxidative stress

Displaying 1 entry
GO Term	Evidence Code	PMID
Golgi cisterna membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

Golgi cisterna membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
glycoprotein 6-alpha-L-fucosyltransferase activity	ISS
glycoprotein 6-alpha-L-fucosyltransferase activity	ISO
glycoprotein 6-alpha-L-fucosyltransferase activity	IEA
glycosyltransferase activity	ISO
SH3 domain binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

hexosyltransferase activity [inference]

fucosyltransferase activity [inference]

alpha-(1->6)-fucosyltransferase activity

glycoprotein 6-alpha-L-fucosyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

glycoprotein 6-alpha-L-fucosyltransferase activity

binding [inference]

protein binding [inference]

protein domain specific binding [inference]

SH3 domain binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

alpha-(1,6)-fucosyltransferase

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
N-glycan fucosylation
SH3 domain binding
alpha-(1->6)-fucosyltransferase activity
glycoprotein 6-alpha-L-fucosyltransferase activity
hexosyltransferase activity
protein N-linked glycosylation
transferase activity

Displaying **all 6** entries
InterPro
Alpha-(1,6)-fucosyltransferase, N- and catalytic domain
Alpha-(1,6)-fucosyltransferase, SH3 domain
Alpha-(1,6)-fucosyltransferase
Glycosyltransferase family 23 (GT23) domain
SH3 domain
SH3-like domain superfamily

KEGG BRITE Database

Orthology

K00717

Name

glycoprotein 6-alpha-L-fucosyltransferase [EC:2.4.1.68]

References

8910378

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R09319	2.4.1.68	G61751GZ	G07483YN
R05988	2.4.1.68	G39213VZ	G80858MF

Rhea

RHEA:12985

GDP-β-L-fucose

H⁺ + GDP

Enzyme

2.4.1.68

PMID

Ortholog

Displaying entries **71 - 80** of **108** in total

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Species	Gene ID	Orthologous MAtrix
Sinocyclocheilus grahami	107553275	SINGR65859
Sinocyclocheilus grahami	107559123	SINGR40803
Sinocyclocheilus grahami	107592788	SINGR53024
Kryptolebias marmoratus	108233337	KRYMA07525
Ictalurus punctatus	108257543	ICTPU20510
Ictalurus punctatus	108270174	ICTPU35020
Rhinopithecus bieti	108542431	RHIBE16559
Cyprinus carpio carpio	109048026	CYPCA89017
Cyprinus carpio carpio	109072175	CYPCA101102
Cyprinus carpio carpio	109087882	CYPCA83338