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cleavage and polyadenylation specific factor 6

Summary

Gene Symbol

Cpsf6

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

432508

PubChem

432508

Alliance of Genome Resources

MGI:1913948

Annotation

Keyword

Cytoplasm
Methylation
Nucleus
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome
mRNA processing

Proteins

Displaying **all 3** entries
UniProt	Protein Name
H3BJW3
H3BJ30
Q6NVF9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
mRNA alternative polyadenylation	IBA ISO ISS
co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway	ISO ISS
protein tetramerization	ISO
mRNA processing	ISO
positive regulation of RNA export from nucleus	ISO ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing

mRNA 3'-end processing

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing

mRNA 3'-end processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing

mRNA 3'-end processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing

mRNA 3'-end processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing

mRNA 3'-end processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing

mRNA 3'-end processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing

mRNA 3'-end processing

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing

mRNA 3'-end processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing

mRNA 3'-end processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA 3'-end processing

RNA 3'-end processing [inference]

mRNA 3'-end processing

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

mRNA metabolic process [inference]

mRNA processing

mRNA 3'-end processing

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein tetramerization

protein heterotetramerization

protein heterooligomerization [inference]

protein heterotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein tetramerization

protein heterotetramerization

protein heterooligomerization [inference]

protein heterotetramerization

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of nucleobase-containing compound transport [inference]

positive regulation of nucleobase-containing compound transport [inference]

positive regulation of RNA export from nucleus

regulation of RNA export from nucleus [inference]

positive regulation of RNA export from nucleus

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of RNA export from nucleus [inference]

positive regulation of RNA export from nucleus

positive regulation of transport [inference]

positive regulation of nucleobase-containing compound transport [inference]

positive regulation of RNA export from nucleus

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of RNA export from nucleus [inference]

positive regulation of RNA export from nucleus

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

positive regulation of transport [inference]

positive regulation of nucleobase-containing compound transport [inference]

positive regulation of RNA export from nucleus

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of RNA export from nucleus

regulation of RNA export from nucleus [inference]

positive regulation of RNA export from nucleus

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
paraspeckles	ISO ISS
nuclear speck	ISO ISS
ribonucleoprotein complex	ISO	18809582
perichromatin fibrils	ISO ISS
interchromatin granule	ISO ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

mRNA cleavage factor complex

mRNA cleavage and polyadenylation specificity factor complex

ribonucleoprotein complex

cellular anatomical entity [inference]

nuclear body [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	29799838
exon-exon junction complex binding	ISO ISS
mRNA binding	IBA ISO ISS
RNA binding	ISO
ribosomal large subunit binding	ISO ISS

GO Hierarchy

molecular function

binding [inference]

protein binding

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

ribosome binding [inference]

ribosomal large subunit binding

exon-exon junction complex binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

mRNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

cleavage and polyadenylation specificity factor subunit 6

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
mRNA alternative polyadenylation

Displaying **all 5** entries
InterPro
CPSF6/7 family
Cleavage and polyadenylation specificity factor subunit 6, RNA recognition motif
Nucleotide-binding alpha-beta plait domain superfamily
RNA recognition motif domain
RNA-binding domain superfamily

Ortholog

Displaying entries **1 - 10** of **115** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	11052		HGNC:13871	HUMAN14204
Drosophila melanogaster	38937		FB:FBgn0035872
Caenorhabditis elegans	177710		WB:WBGene00008362
Rattus norvegicus	299811	10116_1:0028ad	RGD:1304640	RATNO37701
Danio rerio	327069		ZFIN:ZDB-GENE-030131-5277	DANRE33349
Pan troglodytes	452068			PANTR06370
Canis lupus familiaris	474441			CANLF01410
Xenopus tropicalis	548671		Xenbase:XB-GENE-961703
Macaca mulatta	718331			MACMU04106
Monodelphis domestica	100013834			MONDO34340