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MN1 proto-oncogene, transcriptional regulator

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

4330

PubChem

4330

Alliance of Genome Resources

HGNC:7180

Annotation

Keyword

Acetylation
Activator
Chromosomal rearrangement
Developmental protein
Disease variant
Intellectual disability
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Transcription regulation
Tumor suppressor

Proteins

Displaying 1 entry
UniProt	Protein Name
Q10571	Probable tumor suppressor protein MN1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
intramembranous ossification	IEA
regulation of DNA-templated transcription	IEA
regulation of transcription, DNA-templated	IEA
negative regulation of osteoblast proliferation	IDA	15890672
positive regulation of vitamin D receptor signaling pathway	IDA	15890672

GO Hierarchy

biological process

multicellular organismal process [inference]

ossification [inference]

direct ossification [inference]

intramembranous ossification

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of vitamin D receptor signaling pathway

regulation of vitamin D receptor signaling pathway [inference]

positive regulation of vitamin D receptor signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of vitamin D receptor signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of vitamin D receptor signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of vitamin D receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of vitamin D receptor signaling pathway

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of osteoblast proliferation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of vitamin D receptor signaling pathway

regulation of vitamin D receptor signaling pathway [inference]

positive regulation of vitamin D receptor signaling pathway

regulation of response to external stimulus [inference]

regulation of response to extracellular stimulus [inference]

regulation of response to nutrient levels [inference]

regulation of vitamin D receptor signaling pathway [inference]

positive regulation of vitamin D receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of vitamin D receptor signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of vitamin D receptor signaling pathway

regulation of vitamin D receptor signaling pathway [inference]

positive regulation of vitamin D receptor signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of vitamin D receptor signaling pathway

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of osteoblast proliferation

regulation of osteoblast proliferation [inference]

negative regulation of osteoblast proliferation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of vitamin D receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of osteoblast proliferation

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of cell cycle phase transition [inference]

regulation of cell cycle G1/S phase transition

Displaying 1 entry
GO Term	Evidence Code	PMID
nucleus	IDA	31839203

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	31839203

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

MN1

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
InterPro
Transcriptional activator MN1

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:3565	meningioma	Alliance of Genome Resources
DOID:4586	familial meningioma	Alliance of Genome Resources
DOID:8692	myeloid leukemia	Alliance of Genome Resources