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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
MPL proto-oncogene, thrombopoietin receptor
Summary
- Gene Symbol
-
- MPL
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Golgi apparatus
- Isopeptide bond
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P40238 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| basophil homeostasis | ||
| eosinophil homeostasis | ||
| immunoglobulin mediated immune response | ||
| thrombopoietin-mediated signaling pathway | ||
| monocyte homeostasis |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| nuclear membrane | ||
| Golgi apparatus | ||
| neuronal cell body | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| thrombopoietin receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Thrombopoietin receptor
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| thrombopoietin receptor activity |
| InterPro |
|---|
| Fibronectin type III superfamily |
| Fibronectin type III |
| Growth hormone/erythropoietin receptor, ligand binding |
| Immunoglobulin-like fold |
Disease
- Disease Ontology
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 17480 | MGI:97076 | MOUSE41402 | ||
| 366455 | RGD:1311069 | RATNO34520 | ||
| 445381 | ZFIN:ZDB-GENE-060421-1 | DANRE38697 | ||
| 528492 | BOVIN27142 | |||
| 702317 | MACMU22609 | |||
| 747522 | 9598_0:0000ac | |||
| 100409031 | CALJA41368 | |||
| 100448006 | 9601_0:0005e8 | PONAB20146 | ||
| 100476412 | AILME06265 | |||
| 100667327 | LOXAF09274 |
