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apolipophorin

Summary

Gene Symbol

apolpp

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

43827

PubChem

43827

Alliance of Genome Resources

FB:FBgn0087002

Annotation

Keyword

Cell projection
Cleavage on pair of basic residues
Direct protein sequencing
Glycoprotein
Heme
Lipid transport
Lipid-binding
Lipoprotein
Proteomics identification
Reference proteome
Secreted
Signal
Transport
Wnt signaling pathway

Proteins

Displaying **all 2** entries
UniProt	Protein Name
L0MPS3
Q9V496	Retinoid- and fatty acid-binding glycoprotein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
lipid transport	IDA	8742826
lipid transport	IMP	15875013 22844248
lipid transport	IEA
lipid transport involved in lipid storage	IMP	31422916
Wnt signaling pathway

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

lipoprotein localization [inference]

lipoprotein transport

establishment of protein localization [inference]

protein transport [inference]

lipoprotein transport

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

lipoprotein localization [inference]

lipoprotein transport

establishment of protein localization [inference]

protein transport [inference]

lipoprotein transport

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

lipid transport

lipid transport involved in lipid storage

protein transport [inference]

lipoprotein transport

nitrogen compound transport [inference]

protein transport [inference]

lipoprotein transport

establishment of protein localization [inference]

protein transport [inference]

lipoprotein transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

lipoprotein localization [inference]

lipoprotein transport

establishment of protein localization [inference]

protein transport [inference]

lipoprotein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

positive regulation of smoothened signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

positive regulation of smoothened signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

positive regulation of smoothened signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

Displaying **all 5** entries
GO Term	Evidence Code	PMID
extracellular region	NAS	8702812
extracellular space	IDA	22844248 25275323
rhabdomere
endocytic vesicle	IDA	18198278
basal part of cell	IDA	22844248

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

rhabdomere

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle

basal part of cell

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
signaling receptor binding	IPI	18198278
lipid transporter activity	IDA	8742826
lipid transporter activity	IMP	22844248
lipid transporter activity	IBA
lipid transporter activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

lipid transporter activity

binding [inference]

protein binding [inference]

signaling receptor binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

lipid binding [inference]

fatty acid binding

isoprenoid binding [inference]

retinoid binding [inference]

retinol binding

small molecule binding [inference]

vitamin binding [inference]

retinol binding

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

fatty acid binding

alcohol binding [inference]

retinol binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

fatty acid binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Apolipophorin

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
lipid transport
lipid transporter activity

Displaying **all 2** entries
InterPro
Lipid transport protein, beta-sheet shell
Vitellogenin, N-terminal

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
extracellular space	PMID:22844248 PMID:25275323
endocytic vesicle	PMID:18198278
basal part of cell	PMID:22844248
membrane	FB:FBrf0231198

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1682	congenital heart disease	Alliance of Genome Resources

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Danio rerio	338	ZFIN:ZDB-GENE-030131-9732
Danio rerio	43827	ZFIN:ZDB-GENE-070702-4
Danio rerio	54225	ZFIN:ZDB-GENE-030131-9732
Danio rerio	238055	ZFIN:ZDB-GENE-030131-9732