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MIRAGE
CF transmembrane conductance regulator
Summary
- Gene Symbol
-
- CFTR
- Organism
- Ovis aries (sheep)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Cell membrane
- Chloride channel
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Isomerase
- Isopeptide bond
- Nucleus
- Palmitate
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| Q00555 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cholesterol biosynthetic process |
|
|
| vesicle docking involved in exocytosis |
|
|
| bicarbonate transport | ||
| cholesterol transport |
|
|
| response to endoplasmic reticulum stress |
|
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
homeostatic process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
regulation of secretion [inference]
positive regulation of transport [inference]
regulation of cellular localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of transmembrane transport [inference]
positive regulation of cellular process [inference]
regulation of cellular localization [inference]
regulation of biological quality [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus |
|
|
| early endosome |
|
|
| endoplasmic reticulum membrane |
|
|
| cytosol | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| chloride channel activity | ||
| intracellularly ATP-gated chloride channel activity |
|
|
| ATP binding | ||
| bicarbonate transmembrane transporter activity |
|
|
| chloride transmembrane transporter activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- multidrug resistance-associated
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ABC-type transporter activity |
| ATP binding |
| nucleotide binding |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 102179446 | CAPHI23754 | ||
| 102346483 | LATCH07296 | ||
| 102419125 | MYOLU12453 | ||
| 102527896 | VICPA01701 | ||
| 103032690 | ASTMX10261 | ||
| 103179362 | CALMI17668 | ||
| 103264109 | CARSF02782 | ||
| 103676590 | URSMA18815 | ||
| 103737361 | NANGA10908 | ||
| 103813684 | SERCA06162 |
