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serine hydroxymethyltransferase 1

Summary

Gene Symbol

SHMT1

Organism

Ovis aries (sheep)

External Links

NCBI Gene: 443544
KEGG Gene ID: oas:443544
PubChem: 443544

Annotation

Keyword

Acetylation
Cytoplasm
Direct protein sequencing
One-carbon metabolism
Pyridoxal phosphate
Reference proteome
Transferase

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A6P7EF41
P35623	Glycine hydroxymethyltransferase Serine methylase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 7** of 7 in total

« First

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1

2
GO Term	Evidence Code	PMID
purine nucleobase biosynthetic process	IEA	30032202
glycine biosynthetic process from serine	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

amide metabolic process [inference]

folic acid metabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

aromatic compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic cyclic compound biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

aromatic compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

one-carbon metabolic process [inference]

tetrahydrofolate interconversion

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

aromatic compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

one-carbon metabolic process [inference]

tetrahydrofolate interconversion

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

folic acid metabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic cyclic compound biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

aromatic compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

one-carbon metabolic process [inference]

tetrahydrofolate interconversion

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

aromatic compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

response to leukemia inhibitory factor [inference]

cellular response to leukemia inhibitory factor

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleus	IEA	30032202
cytosol	IEA	30032202
cytoplasm	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
zinc ion binding	IEA	30032202
glycine hydroxymethyltransferase activity	IEA	22301074 30032202
protein homodimerization activity	IEA	30032202
mRNA 5'-UTR binding	IEA	30032202
pyridoxal phosphate binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

hydroxymethyl-, formyl- and related transferase activity [inference]

glycine hydroxymethyltransferase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

vitamin binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

organic acid binding [inference]

carboxylic acid binding [inference]

amino acid binding [inference]

serine binding

heterocyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

pyridoxal phosphate binding

carboxylic acid binding [inference]

amino acid binding [inference]

serine binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

serine binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

mRNA binding [inference]

mRNA 5'-UTR binding

translation regulator activity, nucleic acid binding [inference]

mRNA regulatory element binding translation repressor activity

vitamin B6 binding [inference]

pyridoxal phosphate binding

translation regulator activity [inference]

translation repressor activity [inference]

mRNA regulatory element binding translation repressor activity

translation regulator activity, nucleic acid binding [inference]

mRNA regulatory element binding translation repressor activity

Gene Ontology information from NCBI Gene and UniProt.

Rhea

H₂O + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine

L-serine + (6S)-5,6,7,8-tetrahydrofolate

Enzyme

2.1.2.1

PMID

Ortholog

Displaying entries **21 - 30** of 71 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Pan paniscus	100969107		PANPA17260
Pan troglodytes	454490		PANTR14649
Pongo abelii	100171460		PONAB11711
Homo sapiens	6470		HUMAN32191
Canis lupus familiaris	489536		CANLF15579
Ailuropoda melanoleuca	100471874		AILME08824
Mustela putorius furo	101670010		MUSPF03104
Felis catus	101086266		FELCA31698
Panthera leo	122206556		PANLE04827
Tursiops truncatus	101338846		TURTR07853

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024