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aspartate beta-hydroxylase
Summary
- Gene Symbol
-
- ASPH
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Dioxygenase
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Iron
- Metal-binding
- Phosphoprotein
- Reference proteome
- Repeat
- Sarcoplasmic reticulum
- Signal-anchor
- TPR repeat
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| detection of calcium ion | ||
| muscle contraction | ||
| pattern specification process | ||
| cell population proliferation | ||
| negative regulation of cell population proliferation |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of transmembrane transporter activity [inference]
positive regulation of transmembrane transport [inference]
regulation of monoatomic ion transmembrane transport [inference]
positive regulation of monoatomic ion transmembrane transport [inference]
regulation of monoatomic cation transmembrane transport [inference]
regulation of calcium ion transmembrane transport [inference]
regulation of release of sequestered calcium ion into cytosol [inference]
regulation of calcium ion transmembrane transporter activity [inference]
regulation of monoatomic ion transport [inference]
regulation of metal ion transport [inference]
regulation of calcium ion transport [inference]
regulation of calcium ion transmembrane transport [inference]
regulation of release of sequestered calcium ion into cytosol [inference]
regulation of calcium ion transmembrane transporter activity [inference]
regulation of monoatomic ion transmembrane transport [inference]
positive regulation of monoatomic ion transmembrane transport [inference]
regulation of monoatomic cation transmembrane transport [inference]
regulation of calcium ion transmembrane transport [inference]
regulation of release of sequestered calcium ion into cytosol [inference]
regulation of calcium ion transmembrane transporter activity [inference]
positive regulation of monoatomic ion transport [inference]
positive regulation of transport [inference]
regulation of sequestering of calcium ion [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of transport [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of transmembrane transport [inference]
regulation of transmembrane transporter activity [inference]
positive regulation of transmembrane transport [inference]
regulation of monoatomic ion transmembrane transport [inference]
positive regulation of monoatomic ion transmembrane transport [inference]
regulation of monoatomic cation transmembrane transport [inference]
regulation of calcium ion transmembrane transport [inference]
regulation of release of sequestered calcium ion into cytosol [inference]
regulation of calcium ion transmembrane transporter activity [inference]
positive regulation of cellular process [inference]
regulation of sequestering of calcium ion [inference]
regulation of molecular function [inference]
regulation of transporter activity [inference]
positive regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum | ||
| endoplasmic reticulum | ||
| endoplasmic reticulum membrane | ||
| endoplasmic reticulum membrane | ||
| endoplasmic reticulum membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| structural molecule activity | ||
| calcium ion binding | ||
| calcium ion binding | ||
| protein binding | ||
| structural constituent of muscle |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- beta-hydroxylase
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| InterPro |
|---|
| Aspartyl/asparaginy/proline hydroxylase |
| Aspartyl/asparaginyl beta-hydroxylase family |
| Isopenicillin N synthase-like superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4947 | cholangiocarcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 444 | ZFIN:ZDB-GENE-031112-5 | ||
| 65973 | ZFIN:ZDB-GENE-120727-22 | MOUSE42558 | |
| 286771 | BOVIN05880 | ||
| 312981 | RATNO34841 | ||
| 403846 | CANLF11677 | ||
| 464202 | PANTR42641 | ||
| 559236 | DANRE41924 | ||
| 699884 | MACMU44162 | ||
| 100082566 | ORNAN24049 | ||
| 100189667 | PONAB34410 |
