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tollo

Summary

Gene Symbol

Tollo

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

44497

PubChem

44497

Alliance of Genome Resources

FB:FBgn0029114

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Innate immunity
Leucine-rich repeat
NAD
Neurogenesis
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9V477	Toll-like receptor 8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
axis elongation	IGI	25363762
signal transduction	IMP	31088910
signal transduction	IBA
signal transduction	IEA
innate immune response

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

cellular process [inference]

signal transduction

cellular developmental process [inference]

cell development [inference]

neuron development [inference]

peripheral nervous system neuron development

developmental process [inference]

anatomical structure morphogenesis [inference]

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

convergent extension

anatomical structure development [inference]

cell development [inference]

neuron development [inference]

peripheral nervous system neuron development

cellular developmental process [inference]

cell development [inference]

neuron development [inference]

peripheral nervous system neuron development

growth [inference]

developmental growth [inference]

developmental growth involved in morphogenesis [inference]

axis elongation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of glycoprotein biosynthetic process [inference]

regulation of protein glycosylation

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of glycoprotein biosynthetic process [inference]

regulation of protein glycosylation

regulation of nitrogen compound metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein glycosylation

regulation of glycoprotein metabolic process [inference]

regulation of glycoprotein biosynthetic process [inference]

regulation of protein glycosylation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of glycoprotein biosynthetic process [inference]

regulation of protein glycosylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein glycosylation

regulation of glycoprotein metabolic process [inference]

regulation of glycoprotein biosynthetic process [inference]

regulation of protein glycosylation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein glycosylation

regulation of glycoprotein metabolic process [inference]

regulation of glycoprotein biosynthetic process [inference]

regulation of protein glycosylation

regulation of cellular process [inference]

signal transduction

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of glycoprotein biosynthetic process [inference]

regulation of protein glycosylation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IDA	36890234
apical plasma membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
receptor ligand activity	IPI	36890234
NAD+ nucleotidase, cyclic ADP-ribose generating

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

NAD+ nucleosidase activity [inference]

NAD+ nucleotidase, cyclic ADP-ribose generating

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor ligand activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

kinase

Functional Category

O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
Leucine-rich repeat domain superfamily
Leucine-rich repeat, typical subtype
Leucine-rich repeat

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
plasma membrane	PMID:36890234

Ortholog

Displaying entries **21 - 22** of 22 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	445318	WB:WBGene00006593
Caenorhabditis elegans	558825	WB:WBGene00006593

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements