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interleukin 22 receptor subunit alpha 2

Summary

Gene Symbol

Il22ra2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

444986

PubChem

444986

Alliance of Genome Resources

RGD:1303169

Annotation

Keyword

Disulfide bond
Glycoprotein
Receptor
Reference proteome
Repeat
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6JPB3
Q7TNI4	Cytokine receptor family type 2, soluble 1 Interleukin-22-binding protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
regulation of tyrosine phosphorylation of STAT protein	ISO
interleukin-22-mediated signaling pathway	IEA
negative regulation of inflammatory response	IEA ISO
cytokine-mediated signaling pathway	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

interleukin-22-mediated signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein

regulation of nitrogen compound metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein

regulation of macromolecule metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein

negative regulation of biological process [inference]

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

interleukin-22-mediated signaling pathway

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA
extracellular region	IEA
cytosol	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
interleukin-22 receptor activity	IBA IEA ISO
interleukin-22 binding	IEA ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytokine binding [inference]

interleukin-22 binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

interleukin-22 receptor activity

immune receptor activity [inference]

cytokine receptor activity [inference]

interleukin-22 receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

interleukin-22 receptor subunit alpha-2

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
X: Mobilome: prophages, transposons

Displaying **all 4** entries
InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin-like fold
Interferon/interleukin receptor domain

Ortholog

Displaying entries **1 - 10** of **107** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	116379		HGNC:14901	HUMAN86741
Mus musculus	237310	10090_1:00310e	MGI:2665114	MOUSE02063
Pan troglodytes	472133			PANTR39169
Bos taurus	533061			BOVIN35867
Danio rerio	692307		ZFIN:ZDB-GENE-060512-349	DANRE05281
Macaca mulatta	711059			MACMU33947
Equus caballus	100073194			HORSE02809
Taeniopygia guttata	100225166			TAEGU20756
Oryctolagus cuniculus	100341531			RABIT02875
Callithrix jacchus	100386163			CALJA31468