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argininosuccinate synthase 1

Summary

Gene Symbol

ASS1

Organism

Homo sapiens (human)

External Links

NCBI Gene

445

PubChem

445

Alliance of Genome Resources

HGNC:758

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Arginine biosynthesis
Cytoplasm
Direct protein sequencing
Disease variant
Ligase
Phosphoprotein
Reference proteome
Urea cycle

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q5T6L4	Citrulline--aspartate ligase
P00966	Citrulline--aspartate ligase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 35 in total

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GO Term	Evidence Code	PMID
urea cycle	IMP	18473344 27287393 7977368 8792870
urea cycle	IBA
urea cycle	IEA
citrulline metabolic process	IMP	7977368
argininosuccinate metabolic process	IMP	7977368

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

urea cycle

amide metabolic process [inference]

urea metabolic process [inference]

urea cycle

amide biosynthetic process [inference]

urea cycle

nitrogen cycle metabolic process [inference]

urea metabolic process [inference]

urea cycle

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine biosynthetic process

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

aspartate family amino acid metabolic process [inference]

aspartate metabolic process

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

cellular modified amino acid metabolic process [inference]

argininosuccinate metabolic process

urea metabolic process [inference]

urea cycle

organonitrogen compound biosynthetic process [inference]

urea cycle

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

urea cycle

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

organonitrogen compound biosynthetic process [inference]

urea cycle

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine biosynthetic process

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

aspartate family amino acid metabolic process [inference]

aspartate metabolic process

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

dicarboxylic acid metabolic process [inference]

aspartate metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

tricarboxylic acid metabolic process [inference]

argininosuccinate metabolic process

cellular modified amino acid metabolic process [inference]

argininosuccinate metabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

urea cycle

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

urea cycle

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine biosynthetic process

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

aspartate family amino acid metabolic process [inference]

aspartate metabolic process

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine biosynthetic process

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

aspartate family amino acid metabolic process [inference]

aspartate metabolic process

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

dicarboxylic acid metabolic process [inference]

aspartate metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

tricarboxylic acid metabolic process [inference]

argininosuccinate metabolic process

urea metabolic process [inference]

urea cycle

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine biosynthetic process

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

aspartate family amino acid metabolic process [inference]

aspartate metabolic process

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

dicarboxylic acid metabolic process [inference]

aspartate metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

tricarboxylic acid metabolic process [inference]

argininosuccinate metabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine biosynthetic process

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

aspartate family amino acid metabolic process [inference]

aspartate metabolic process

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

cellular modified amino acid metabolic process [inference]

argininosuccinate metabolic process

urea metabolic process [inference]

urea cycle

organonitrogen compound biosynthetic process [inference]

urea cycle

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

organonitrogen compound biosynthetic process [inference]

urea cycle

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine biosynthetic process

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

aspartate family amino acid metabolic process [inference]

aspartate metabolic process

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

dicarboxylic acid metabolic process [inference]

aspartate metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

tricarboxylic acid metabolic process [inference]

argininosuccinate metabolic process

cellular modified amino acid metabolic process [inference]

argininosuccinate metabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

urea cycle

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

urea cycle

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to fluid shear stress [inference]

cellular response to laminar fluid shear stress

cellular response to chemical stimulus [inference]

cellular response to acid chemical [inference]

cellular response to amino acid stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to cytokine stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to fatty acid [inference]

cellular response to oleic acid

cellular response to organic cyclic compound [inference]

cellular response to cAMP

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to nitrogen compound [inference]

cellular response to ammonium ion

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to oxygen-containing compound [inference]

cellular response to fatty acid [inference]

cellular response to oleic acid

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

developmental process [inference]

anatomical structure development [inference]

tube development [inference]

digestive tract development [inference]

midgut development

animal organ development [inference]

kidney development

muscle organ development [inference]

skeletal muscle organ development [inference]

diaphragm development

gland development [inference]

liver development

muscle structure development [inference]

muscle organ development [inference]

skeletal muscle organ development [inference]

diaphragm development

rhythmic process [inference]

circadian rhythm

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

acute inflammatory response [inference]

acute-phase response

cellular response to stress [inference]

cellular response to fluid shear stress [inference]

cellular response to laminar fluid shear stress

response to fluid shear stress [inference]

response to laminar fluid shear stress [inference]

cellular response to laminar fluid shear stress

cellular response to fluid shear stress [inference]

cellular response to laminar fluid shear stress

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to peptide hormone [inference]

response to glucagon [inference]

cellular response to glucagon stimulus

response to growth hormone

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

response to chemical [inference]

response to acid chemical [inference]

response to amino acid [inference]

cellular response to amino acid stimulus

cellular response to acid chemical [inference]

cellular response to amino acid stimulus

response to toxic substance [inference]

response to mycotoxin

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to peptide hormone [inference]

response to glucagon [inference]

cellular response to glucagon stimulus

response to growth hormone

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to organonitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

response to amine [inference]

cellular response to amine stimulus

response to amino acid [inference]

cellular response to amino acid stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

response to peptide [inference]

response to peptide hormone [inference]

response to glucagon [inference]

cellular response to glucagon stimulus

response to growth hormone

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

response to organic cyclic compound [inference]

response to purine-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

response to estradiol

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to organic cyclic compound [inference]

cellular response to cAMP

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to lipid [inference]

response to estradiol

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

response to fatty acid [inference]

response to oleic acid [inference]

cellular response to oleic acid

cellular response to fatty acid [inference]

cellular response to oleic acid

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to fatty acid [inference]

cellular response to oleic acid

response to cytokine [inference]

response to type II interferon [inference]

cellular response to type II interferon

response to tumor necrosis factor [inference]

cellular response to tumor necrosis factor

cellular response to cytokine stimulus [inference]

response to organophosphorus [inference]

response to cAMP [inference]

cellular response to cAMP

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to cytokine stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to fatty acid [inference]

cellular response to oleic acid

cellular response to organic cyclic compound [inference]

cellular response to cAMP

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

response to ketone [inference]

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

response to inorganic substance [inference]

response to metal ion [inference]

response to zinc ion

response to ammonium ion [inference]

cellular response to ammonium ion

cellular response to chemical stimulus [inference]

cellular response to acid chemical [inference]

cellular response to amino acid stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to cytokine stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to fatty acid [inference]

cellular response to oleic acid

cellular response to organic cyclic compound [inference]

cellular response to cAMP

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to nitrogen compound [inference]

cellular response to ammonium ion

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to oxygen-containing compound [inference]

cellular response to fatty acid [inference]

cellular response to oleic acid

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

response to amine [inference]

cellular response to amine stimulus

response to amino acid [inference]

cellular response to amino acid stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

response to peptide [inference]

response to peptide hormone [inference]

response to glucagon [inference]

cellular response to glucagon stimulus

response to growth hormone

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

response to ammonium ion [inference]

cellular response to ammonium ion

cellular response to nitrogen compound [inference]

cellular response to ammonium ion

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

response to oxygen-containing compound [inference]

response to estradiol

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

response to amino acid [inference]

cellular response to amino acid stimulus

response to cAMP [inference]

cellular response to cAMP

response to fatty acid [inference]

response to oleic acid [inference]

cellular response to oleic acid

cellular response to fatty acid [inference]

cellular response to oleic acid

response to peptide [inference]

response to peptide hormone [inference]

response to glucagon [inference]

cellular response to glucagon stimulus

response to growth hormone

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

response to ketone [inference]

response to dexamethasone [inference]

cellular response to dexamethasone stimulus

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to fatty acid [inference]

cellular response to oleic acid

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to fluid shear stress [inference]

cellular response to laminar fluid shear stress

cellular response to chemical stimulus [inference]

cellular response to acid chemical [inference]

cellular response to amino acid stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to cytokine stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to fatty acid [inference]

cellular response to oleic acid

cellular response to organic cyclic compound [inference]

cellular response to cAMP

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus [inference]

cellular response to dexamethasone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to nitrogen compound [inference]

cellular response to ammonium ion

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to oxygen-containing compound [inference]

cellular response to fatty acid [inference]

cellular response to oleic acid

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to glucagon stimulus

cellular response to ketone [inference]

cellular response to dexamethasone stimulus

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of cellular biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of cellular biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide metabolic process [inference]

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion

regulation of cellular process [inference]

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion

regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of cellular biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
perikaryon	IEA
extracellular exosome	HDA	19056867 23533145
cell body fiber	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

cell body fiber

perikaryon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
RNA binding	HDA	22658674
argininosuccinate synthase activity	IMP	18473344 27287393 28985504 7977368 8792870
argininosuccinate synthase activity	IBA
protein binding	IPI	12620389 17496144 28587924 28985504
ATP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

ligase activity [inference]

ligase activity, forming carbon-nitrogen bonds [inference]

argininosuccinate synthase activity

binding [inference]

protein binding

identical protein binding

toxic substance binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

amino acid binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

amino acid binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

argininosuccinate

Functional Category

E: Amino acid transport and metabolism
F: Nucleotide transport and metabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
amino acid biosynthetic process
arginine biosynthetic process
argininosuccinate metabolic process
argininosuccinate synthase activity
ligase activity
nucleotide binding

Displaying **all 7** entries
InterPro
Argininosuccinate synthase, conserved site
Argininosuccinate synthase, type 1 subfamily
Argininosuccinate synthase
Argininosuccinate synthetase, catalytic/multimerisation domain body
Arginosuccinate synthase C-terminal domain
Arginosuccinate synthase-like, N-terminal domain
Rossmann-like alpha/beta/alpha sandwich fold

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0070340	classic citrullinemia	Alliance of Genome Resources
DOID:1909	melanoma	Alliance of Genome Resources
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources
DOID:9273	citrullinemia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	445	Xenbase:XB-GENE-977784
Mus musculus	11898	Xenbase:XB-GENE-977784	MOUSE33496
Rattus norvegicus	25698		RATNO28227
Bos taurus	280726		BOVIN03304
Sus scrofa	414411		PIGXX16343
Canis lupus familiaris	480693		CANLF19357
Macaca mulatta	716168		MACMU13493
Pan troglodytes	743223		PANTR45055
Monodelphis domestica	100013289		MONDO05628
Taeniopygia guttata	100218639		TAEGU06537

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements