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fucosyltransferase 8

Summary

Gene Symbol

FUT8

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 449506
KEGG Gene ID: ptr:449506
PubChem: 449506

Annotation

Keyword

Coiled coil
Disulfide bond
Glycosyltransferase
Golgi apparatus
Phosphoprotein
Reference proteome
SH3 domain
SH3-binding
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
K7ASB1
A0A663DA72
Q6EV77	Fucosyltransferase 8 GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase GDP-fucose--glycoprotein fucosyltransferase Glycoprotein 6-alpha-L-fucosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein N-linked glycosylation	IEA	30032202
protein N-linked glycosylation via asparagine
N-glycan fucosylation	IEA	30032202
GDP-L-fucose metabolic process

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

phosphorus metabolic process [inference]

GDP-L-fucose metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

glycosylation [inference]

fucosylation [inference]

N-glycan fucosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

carbohydrate derivative metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

phosphorus metabolic process [inference]

GDP-L-fucose metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

GDP-L-fucose metabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
Golgi cisterna membrane	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

Golgi cisterna membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IEA	22301074
glycoprotein 6-alpha-L-fucosyltransferase activity	IEA	22301074
SH3 domain binding
alpha-(1->6)-fucosyltransferase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

fucosyltransferase activity [inference]

alpha-(1->6)-fucosyltransferase activity

glycoprotein 6-alpha-L-fucosyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

glycoprotein 6-alpha-L-fucosyltransferase activity

binding [inference]

protein binding

protein domain specific binding [inference]

SH3 domain binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level: Hominidae
Group Name: alpha-(1,6)-fucosyltransferase

Displaying entries **1 - 10** of 17 in total

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Gene Ontology
GDP-L-fucose metabolic process
N-glycan fucosylation
SH3 domain binding
alpha-(1->6)-fucosyltransferase activity
cell migration
fibroblast migration
glycoprotein 6-alpha-L-fucosyltransferase activity
hexosyltransferase activity
integrin-mediated signaling pathway
protein N-linked glycosylation via asparagine

Displaying **all 6** entries
InterPro
Alpha-(1,6)-fucosyltransferase, N- and catalytic domain
Alpha-(1,6)-fucosyltransferase, SH3 domain
Alpha-(1,6)-fucosyltransferase
Glycosyltransferase family 23 (GT23) domain
SH3 domain
SH3-like domain superfamily

KEGG BRITE Database

Orthology

K00717

Name

glycoprotein 6-alpha-L-fucosyltransferase [EC:2.4.1.68]

References

8910378

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R09319	2.4.1.68	G61751GZ	G07483YN
R05988	2.4.1.68	G39213VZ	G80858MF

Rhea

RHEA:12985

GDP-β-L-fucose

H⁺ + GDP

Enzyme

2.4.1.68

PMID

Ortholog

Displaying entries **61 - 70** of **102** in total

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Species	Gene ID	Orthologous MAtrix
Propithecus coquereli	105819734	PROCO01196
Dipodomys ordii	105986028	DIPOR01849
Salmo salar	106611223	SALSA144398
Equus asinus asinus	106844896	EQUAS25032
Sinocyclocheilus grahami	107553275	SINGR65859
Sinocyclocheilus grahami	107559123	SINGR40803
Sinocyclocheilus grahami	107592788	SINGR53024
Kryptolebias marmoratus	108233337	KRYMA07525
Ictalurus punctatus	108257543	ICTPU20510
Ictalurus punctatus	108270174	ICTPU35020

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Annotation

OrthoDB (Group)

KEGG BRITE Database

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Acknowledgements