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complement C6

Summary

Gene Symbol

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene

449612

KEGG Gene ID

PubChem

449612

Annotation

Keyword

Calcium
Disulfide bond
EGF-like domain
Glycoprotein
Membrane attack complex
Metal-binding
Reference proteome
Repeat
Secreted
Signal
Sushi
Target cell membrane
Transmembrane beta strand

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2J8QA94
P61134

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

1

2

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GO Term	Evidence Code	PMID
in utero embryonic development
positive regulation of activation of membrane attack complex
complement activation	ISS
complement activation	IBA
complement activation	IEA

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

complement activation

activation of immune response [inference]

complement activation

immune response [inference]

humoral immune response [inference]

complement activation

innate immune response [inference]

complement activation, GZMK pathway

cellular process [inference]

cell killing [inference]

killing of cells of another organism

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

developmental process [inference]

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

animal gross anatomical part developmental process [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

complement activation, GZMK pathway

disruption of anatomical structure in another organism [inference]

disruption of cell in another organism [inference]

killing of cells of another organism

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

complement activation, GZMK pathway

immune response [inference]

humoral immune response [inference]

complement activation

innate immune response [inference]

complement activation, GZMK pathway

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

complement activation, GZMK pathway

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

complement activation, GZMK pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of complement activation [inference]

positive regulation of activation of membrane attack complex

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

positive regulation of humoral immune response [inference]

positive regulation of complement activation [inference]

positive regulation of activation of membrane attack complex

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of complement activation [inference]

positive regulation of activation of membrane attack complex

regulation of complement activation [inference]

regulation of activation of membrane attack complex [inference]

positive regulation of activation of membrane attack complex

positive regulation of complement activation [inference]

positive regulation of activation of membrane attack complex

regulation of immune response [inference]

regulation of humoral immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of complement activation [inference]

positive regulation of activation of membrane attack complex

regulation of complement activation [inference]

regulation of activation of membrane attack complex [inference]

positive regulation of activation of membrane attack complex

positive regulation of complement activation [inference]

positive regulation of activation of membrane attack complex

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

positive regulation of humoral immune response [inference]

positive regulation of complement activation [inference]

positive regulation of activation of membrane attack complex

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of complement activation [inference]

positive regulation of activation of membrane attack complex

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

positive regulation of humoral immune response [inference]

positive regulation of complement activation [inference]

positive regulation of activation of membrane attack complex

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

positive regulation of humoral immune response [inference]

positive regulation of complement activation [inference]

positive regulation of activation of membrane attack complex

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

positive regulation of humoral immune response [inference]

positive regulation of complement activation [inference]

positive regulation of activation of membrane attack complex

regulation of immune response [inference]

regulation of humoral immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of complement activation [inference]

positive regulation of activation of membrane attack complex

regulation of complement activation [inference]

regulation of activation of membrane attack complex [inference]

positive regulation of activation of membrane attack complex

positive regulation of complement activation [inference]

positive regulation of activation of membrane attack complex

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

positive regulation of humoral immune response [inference]

positive regulation of complement activation [inference]

positive regulation of activation of membrane attack complex

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane attack complex	IBA
membrane attack complex	IEA
obsolete extracellular space
other organism cell membrane	IEA
transmembrane transporter complex

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

pore complex [inference]

membrane attack complex

plasma membrane protein complex [inference]

membrane attack complex

transmembrane transporter complex

transporter complex [inference]

transmembrane transporter complex

cellular anatomical structure [inference]

other organism part [inference]

other organism cell membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IEA
metal ion binding

GO Hierarchy

molecular function

binding [inference]

protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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