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C-C motif chemokine receptor 5

Summary

Gene Symbol

CCR5

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 450128
PubChem: 450128

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Palmitate
Phosphoprotein
Reference proteome
Sulfation
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2J8PAG3
P56440

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
calcium-mediated signaling	IEA	30032202
cell chemotaxis	IEA	30032202
immune response	IEA	22301074 30032202
inflammatory response	IEA	22301074
positive regulation of cytosolic calcium ion concentration	IEA	30032202

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

cell motility [inference]

cell migration [inference]

cell chemotaxis

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 3** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IEA	30032202
membrane	IEA	22301074
cytoplasm

GO Hierarchy

cellular component

cellular anatomical entity [inference]

side of membrane [inference]

external side of plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
chemokine (C-C motif) ligand 5 binding	IEA	30032202
C-C chemokine receptor activity	IEA	22301074 30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytokine binding [inference]

chemokine binding [inference]

C-C chemokine binding [inference]

chemokine (C-C motif) ligand 5 binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity [inference]

C-C chemokine receptor activity

G protein-coupled receptor activity [inference]

G protein-coupled chemoattractant receptor activity [inference]

chemokine receptor activity [inference]

C-C chemokine receptor activity

immune receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity [inference]

C-C chemokine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Hominidae

Group Name

C-C chemokine receptor type 5

Functional Category

A: RNA processing and modification
T: Signal transduction mechanisms

Displaying entries **1 - 10** of 18 in total

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Gene Ontology
C-C chemokine binding
C-C chemokine receptor activity
actin binding
calcium ion transport
calcium-mediated signaling
cell chemotaxis
cell-cell signaling
cellular response to lipopolysaccharide
chemokine (C-C motif) ligand 5 binding
chemokine receptor activity

Displaying **all 4** entries
InterPro
CC chemokine receptor 5
Chemokine receptor family
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **41 - 50** of 61 in total

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Species	Gene ID	Orthologous MAtrix
Macaca nemestrina	105480352	MACNE06855
Mandrillus leucophaeus	105540428	MANLE07432
Cercocebus atys	105573604	CERAT32195
Microcebus murinus	105874441	MICMU05126
Dipodomys ordii	105996280	DIPOR21301
Equus caballus	106781824	HORSE12243
Rhinopithecus bieti	108517666	RHIBE15777
Phascolarctos cinereus	110209090	PHACI23183
Phascolarctos cinereus	110209094	PHACI23184
Vulpes vulpes	112912493	VULVU04108