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endothelin receptor type A

Summary

Gene Symbol

EDNRA

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene: 450187
PubChem: 450187

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5KSU9	Endothelin receptor type A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
endothelin receptor signaling pathway
developmental pigmentation
enteric nervous system development	IEA	22301074
regulation of blood pressure	IEA	22301074
vasoconstriction	IEA	22301074

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

endothelin receptor signaling pathway

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

vasoconstriction

developmental process [inference]

anatomical structure development [inference]

system development [inference]

enteric nervous system development

pigmentation [inference]

developmental pigmentation

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

endothelin receptor signaling pathway

regulation of biological quality [inference]

regulation of blood pressure

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

vasoconstriction

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA	22301074
plasma membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
endothelin receptor activity	IEA	22301074

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

endothelin receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

endothelin receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

receptor

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
G protein-coupled peptide receptor activity
neuropeptide receptor activity

Displaying **all 3** entries
InterPro
Bombesin receptor-like
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **111 - 120** of **127** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Puma yagouaroundi	121028820	1608482_0:00003d
Vulpes lagopus	121481257	494514_0:004bdb
Panthera leo	122217808	9689_0:00107a	PANLE27605
Prionailurus bengalensis	122475763	37029_0:0005df
Neogale vison	122889603	452646_0:003e66
Leopardus geoffroyi	123591679	46844_0:000623
Ursus americanus	123793233	9643_0:001e53
Mirounga angustirostris	123848185	9716_0:0012e0
Meles meles	123935025	9662_0:00098e
Lynx rufus	124520812	61384_0:00293b