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ST6 beta-galactoside alpha-2,6-sialyltransferase 2

Summary

Gene Symbol

ST6GAL2

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 450198
KEGG Gene ID: ptr:450198
PubChem: 450198

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A2J8J6X7	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2 ST6Gal II Sialyltransferase 2
A0A6D2VSW5	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2 ST6Gal II Sialyltransferase 2
Q701R4	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2 ST6Gal II Sialyltransferase 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA	22301074
oligosaccharide metabolic process
sialylation	IEA	30032202
protein glycosylation	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

primary metabolic process [inference]

carbohydrate metabolic process

oligosaccharide metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process

oligosaccharide metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

sialylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
Golgi apparatus	IEA	30032202
Golgi cisterna membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

Golgi cisterna membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying 1 entry
GO Term	Evidence Code	PMID
beta-galactoside alpha-2,6-sialyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity [inference]

beta-galactoside alpha-2,6-sialyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00779

Name

beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2) [EC:2.4.3.1]

References

12235148

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R06188	2.4.3.1	G51331BY	G09376MR

Rhea

RHEA:21552

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate

H⁺ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP

Enzyme

2.4.3.1

PMID

2460092

RHEA:11836

N-acetyl-β-lactosamine + CMP-N-acetyl-β-neuraminate

H⁺ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosamine + CMP

Enzyme

2.4.3.1

PMID

RHEA:52104

a β-D-galactoside + CMP-N-acetyl-β-neuraminate

an N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl derivative + H⁺ + CMP

Enzyme

2.4.3.1

PMID

Ortholog

Displaying entries **61 - 65** of 65 in total

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Species	Gene ID	Orthologous MAtrix
Propithecus coquereli	105826334	PROCO05212
Nannospalax galili	103726632	NANGA19256
Corvus moneduloides	116440104	CORMO14673
Carlito syrichta	103258958	CARSF21141
Strigops habroptila	115604040	STRHB00617

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements