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glutamic-oxaloacetic transaminase 1

Summary

Gene Symbol

GOT1

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 450664
PubChem: 450664

Annotation

Keyword

Amino-acid biosynthesis
Aminotransferase
Cytoplasm
Phosphoprotein
Pyridoxal phosphate
Reference proteome

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A5A6K8	Cysteine aminotransferase, cytoplasmic Cysteine transaminase, cytoplasmic Glutamate oxaloacetate transaminase 1 Transaminase A
K7CUW2
A0A663DIG5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
2-oxoglutarate metabolic process
glycerol biosynthetic process
aspartate metabolic process
aspartate biosynthetic process	IEA	30032202
glutamate metabolic process

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

glutamate metabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process

aspartate family amino acid metabolic process [inference]

aspartate metabolic process

aspartate biosynthetic process

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process

aspartate family amino acid metabolic process [inference]

aspartate metabolic process

aspartate biosynthetic process

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid metabolic process [inference]

2-oxoglutarate metabolic process

aspartate metabolic process

aspartate biosynthetic process

glutamate metabolic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol biosynthetic process

alditol biosynthetic process [inference]

glycerol biosynthetic process

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process

aspartate family amino acid metabolic process [inference]

aspartate metabolic process

aspartate biosynthetic process

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol biosynthetic process

alditol biosynthetic process [inference]

glycerol biosynthetic process

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process

aspartate family amino acid metabolic process [inference]

aspartate metabolic process

aspartate biosynthetic process

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid metabolic process [inference]

2-oxoglutarate metabolic process

aspartate metabolic process

aspartate biosynthetic process

glutamate metabolic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol biosynthetic process

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process

aspartate family amino acid metabolic process [inference]

aspartate metabolic process

aspartate biosynthetic process

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid metabolic process [inference]

2-oxoglutarate metabolic process

aspartate metabolic process

aspartate biosynthetic process

glutamate metabolic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process

aspartate family amino acid metabolic process [inference]

aspartate metabolic process

aspartate biosynthetic process

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol biosynthetic process

alditol biosynthetic process [inference]

glycerol biosynthetic process

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process

aspartate family amino acid metabolic process [inference]

aspartate metabolic process

aspartate biosynthetic process

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid metabolic process [inference]

2-oxoglutarate metabolic process

aspartate metabolic process

aspartate biosynthetic process

glutamate metabolic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

aspartate family amino acid biosynthetic process [inference]

aspartate biosynthetic process

dicarboxylic acid biosynthetic process [inference]

aspartate biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
L-aspartate:2-oxoglutarate aminotransferase activity	IEA	30032202
pyridoxal phosphate binding	IEA	22301074
L-cysteine transaminase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring nitrogenous groups [inference]

transaminase activity [inference]

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

heterocyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

pyridoxal phosphate binding

organic cyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

aspartate other aminotransferase

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
L-aspartate
catalytic activity
pyridoxal phosphate binding
transaminase activity
transferase activity

Displaying **all 6** entries
InterPro
Aminotransferase, class I/classII
Aminotransferases, class-I, pyridoxal-phosphate-binding site
Aspartate/other aminotransferase
Pyridoxal phosphate-dependent transferase, major domain
Pyridoxal phosphate-dependent transferase, small domain
Pyridoxal phosphate-dependent transferase

Ortholog

Displaying entries **1 - 10** of 87 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	2805	HUMAN02463
Mus musculus	14718	MOUSE25962
Bos taurus	281206	BOVIN21323
Sus scrofa	396967	PIGXX08310
Canis lupus familiaris	486834	CANLF11375
Macaca mulatta	708434	MACMU46778
Monodelphis domestica	100020894	MONDO05564
Ornithorhynchus anatinus	100076641	ORNAN18013
Pongo abelii	100173864	PONAB01310
Ciona intestinalis	100184965	CIOIN10595

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Acknowledgements