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tripeptidyl peptidase 1
Summary
- Gene Symbol
-
- TPP1
- Organism
- Pan troglodytes (chimpanzee)
Annotation
- Keyword
-
- Autocatalytic cleavage
- Calcium
- Disulfide bond
- Glycoprotein
- Lysosome
- Metal-binding
- Reference proteome
- Serine protease
- Signal
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A663DB92 |
|
| G2HHK8 |
|
| Q5IS74 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| nervous system development |
|
|
| central nervous system development | ||
| peptide catabolic process |
|
|
| bone resorption |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| lysosome |
|
|
| Golgi apparatus |
|
|
| melanosome |
|
|
| membrane raft |
|
|
| recycling endosome |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| endopeptidase activity |
|
|
| serine-type endopeptidase activity | ||
| peptidase activity |
|
|
| serine-type peptidase activity |
|
|
| tripeptidyl-peptidase activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Tripeptidyl peptidase a
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- P: Inorganic ion transport and metabolism
| Gene Ontology |
|---|
| hydrolase activity |
| metal ion binding |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
| tripeptidyl-peptidase activity |
| InterPro |
|---|
| Peptidase S53, activation domain |
| Peptidase S8/S53 domain superfamily |
| Peptidase S8/S53 domain |
| Sedolisin domain |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 1200 | HUMAN04344 | ||
| 12751 | MOUSE52402 | ||
| 83534 | RATNO18209 | ||
| 485337 | CANLF08472 | ||
| 515575 | BOVIN06903 | ||
| 709838 | MACMU10383 | ||
| 798347 | DANRE12913 | ||
| 100030970 | MONDO23702 | ||
| 100070095 | HORSE38706 | ||
| 100232321 | TAEGU11818 |
