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MIRAGE
lactate dehydrogenase A

Summary
Gene Symbol
  • LDHA
Organism
Pan troglodytes (chimpanzee)
NCBI Gene
451063
KEGG Gene ID
ptr:451063
PubChem
451063
Annotation
Keyword
  • Acetylation
  • Cytoplasm
  • Isopeptide bond
  • NAD
  • Oxidoreductase
  • Phosphoprotein
  • Reference proteome
  • Ubl conjugation
Proteins
Displaying all 4 entries
UniProt Protein Name
A0A6D2W142
Q5R1W9
  • LDH muscle subunit
A0A2I3STT4
G2HDZ4
Annotation information from UniProt.
Gene Ontology (GO)
Displaying 1 entry
GO Term Evidence Code PMID
cytoplasm
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
lactate dehydrogenase
Functional Category
  • C: Energy production and conversion
  • E: Amino acid transport and metabolism
  • T: Signal transduction mechanisms
Displaying all 6 entries
Gene Ontology
L-lactate dehydrogenase activity
carboxylic acid metabolic process
catalytic activity
lactate metabolic process
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
oxidoreductase activity
Displaying all 7 entries
InterPro
L-lactate dehydrogenase, active site
L-lactate dehydrogenase
L-lactate/malate dehydrogenase
Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Lactate/malate dehydrogenase, C-terminal
Lactate/malate dehydrogenase, N-terminal
NAD(P)-binding domain superfamily
KEGG BRITE Database
Orthology
K00016
Name
L-lactate dehydrogenase [EC:1.1.1.27]
References
Rhea

RHEA:23444

(S)-lactate + NAD+
pyruvate + H+ + NADH
Enzyme
PMID
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026