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spinster

Summary

Gene Symbol

spin

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

45380

PubChem

45380

Alliance of Genome Resources

FB:FBgn0086676

Annotation

Keyword

Alternative splicing
Developmental protein
Endosome
Glycoprotein
Lipid transport
Lysosome
Oogenesis
Reference proteome
Transmembrane helix
Transport

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9GQQ0	Protein benchwarmer Protein diphthong
R4NR58

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
lipid transport
endocytosis	IMP	15998804
lysosome organization	IMP	21518918
courtship behavior	NAS	11715043
endosome to lysosome transport	IMP	15998804

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cell death [inference]

programmed cell death

apoptotic process [inference]

apoptotic process involved in development [inference]

nurse cell apoptotic process

programmed cell death involved in cell development [inference]

nurse cell apoptotic process

vesicle-mediated transport [inference]

endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

endosome to lysosome transport

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

oogenesis

nurse cell apoptotic process

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

nurse cell apoptotic process

cell differentiation [inference]

glial cell differentiation

cell development [inference]

germ cell development [inference]

oogenesis

cell motility [inference]

cell migration [inference]

glial cell migration

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

lytic vacuole organization [inference]

lysosome organization

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly [inference]

synaptic assembly at neuromuscular junction

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly [inference]

synaptic assembly at neuromuscular junction

synapse organization [inference]

synapse assembly [inference]

synaptic assembly at neuromuscular junction

neuromuscular junction development [inference]

synaptic assembly at neuromuscular junction

reproductive process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

oogenesis

nurse cell apoptotic process

reproductive behavior [inference]

mating behavior [inference]

courtship behavior

female mating behavior [inference]

regulation of female receptivity

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

oogenesis

nurse cell apoptotic process

multicellular organismal reproductive process [inference]

gamete generation [inference]

female gamete generation [inference]

oogenesis

multicellular organismal process [inference]

behavior [inference]

reproductive behavior [inference]

mating behavior [inference]

courtship behavior

female mating behavior [inference]

regulation of female receptivity

developmental process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

oogenesis

nurse cell apoptotic process

anatomical structure morphogenesis [inference]

post-embryonic animal morphogenesis [inference]

larval central nervous system remodeling

anatomical structure development [inference]

cell development [inference]

germ cell development [inference]

oogenesis

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

nurse cell apoptotic process

cell differentiation [inference]

glial cell differentiation

cell development [inference]

germ cell development [inference]

oogenesis

growth [inference]

developmental growth [inference]

synaptic assembly at neuromuscular junction

locomotion

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

endosome to lysosome transport

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

transmembrane transport

organic substance transport [inference]

lipid transport

import into cell [inference]

endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

establishment of localization in cell [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of growth [inference]

regulation of developmental growth [inference]

regulation of synaptic assembly at neuromuscular junction

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of synaptic assembly at neuromuscular junction

regulation of apoptotic process involved in development [inference]

regulation of nurse cell apoptotic process

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of programmed cell death

regulation of apoptotic process [inference]

regulation of apoptotic process involved in development [inference]

regulation of nurse cell apoptotic process

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction

regulation of neuromuscular junction development [inference]

regulation of synaptic assembly at neuromuscular junction

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction

regulation of reproductive process [inference]

regulation of nurse cell apoptotic process

regulation of biological quality [inference]

regulation of female receptivity

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
lysosomal membrane
membrane	ISM	28878041
membrane	IBA
late endosome membrane	IDA	12408844
vesicle	IDA	21562262

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

late endosome membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane [inference]

late endosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle

presynapse

Displaying **all 3** entries
GO Term	Evidence Code	PMID
transmembrane transporter activity	ISM	28878041
transmembrane transporter activity	IBA
transmembrane transporter activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

spinster

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
InterPro
MFS transporter superfamily
Major facilitator superfamily domain
Major facilitator superfamily
Protein spinster-like

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
membrane	FB:FBrf0231198
vesicle	PMID:21562262
late endosome membrane	PMID:12408844

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:14503	neuronal ceroid lipofuscinosis	Alliance of Genome Resources
DOID:1927	sphingolipidosis	Alliance of Genome Resources

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	45380	Xenbase:XB-GENE-5793583
Xenopus tropicalis	83985	Xenbase:XB-GENE-959720
Xenopus tropicalis	124976	Xenbase:XB-GENE-5793583

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements