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spinster

Summary

Gene Symbol

spin

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

45380

PubChem

45380

Alliance of Genome Resources

FB:FBgn0086676

Annotation

Keyword

Alternative splicing
Developmental protein
Endosome
Glycoprotein
Lipid transport
Lysosome
Oogenesis
Reference proteome
Transmembrane helix
Transport

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9GQQ0	Protein benchwarmer Protein diphthong
R4NR58

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 21 in total

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GO Term	Evidence Code	PMID
endosome to lysosome transport	IMP	15998804
glial cell migration	IMP	21562262
regulation of nurse cell apoptotic process	IMP	11340170
transmembrane transport	IEA ISM	28878041
programmed cell death	NAS	11715043

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cell death [inference]

programmed cell death

apoptotic process [inference]

apoptotic process involved in development [inference]

nurse cell apoptotic process

programmed cell death involved in cell development [inference]

nurse cell apoptotic process

vesicle-mediated transport [inference]

endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

endosome to lysosome transport

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

oogenesis

nurse cell apoptotic process

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

nurse cell apoptotic process

cell differentiation [inference]

glial cell differentiation

cell development [inference]

germ cell development [inference]

oogenesis

cell motility [inference]

cell migration [inference]

glial cell migration

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

lytic vacuole organization [inference]

lysosome organization

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly [inference]

synaptic assembly at neuromuscular junction

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly [inference]

synaptic assembly at neuromuscular junction

synapse organization [inference]

synapse assembly [inference]

synaptic assembly at neuromuscular junction

neuromuscular junction development [inference]

synaptic assembly at neuromuscular junction

reproductive process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

oogenesis

nurse cell apoptotic process

reproductive behavior [inference]

mating behavior [inference]

courtship behavior

female mating behavior [inference]

regulation of female receptivity

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

oogenesis

nurse cell apoptotic process

multicellular organismal reproductive process [inference]

gamete generation [inference]

female gamete generation [inference]

oogenesis

multicellular organismal process [inference]

behavior [inference]

reproductive behavior [inference]

mating behavior [inference]

courtship behavior

female mating behavior [inference]

regulation of female receptivity

developmental process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

oogenesis

nurse cell apoptotic process

anatomical structure morphogenesis [inference]

post-embryonic animal morphogenesis [inference]

larval central nervous system remodeling

anatomical structure development [inference]

cell development [inference]

germ cell development [inference]

oogenesis

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

nurse cell apoptotic process

cell differentiation [inference]

glial cell differentiation

cell development [inference]

germ cell development [inference]

oogenesis

growth [inference]

developmental growth [inference]

synaptic assembly at neuromuscular junction

locomotion

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

endosome to lysosome transport

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

transmembrane transport

organic substance transport [inference]

lipid transport

import into cell [inference]

endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

establishment of localization in cell [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of growth [inference]

regulation of developmental growth [inference]

regulation of synaptic assembly at neuromuscular junction

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of synaptic assembly at neuromuscular junction

regulation of apoptotic process involved in development [inference]

regulation of nurse cell apoptotic process

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of programmed cell death

regulation of apoptotic process [inference]

regulation of apoptotic process involved in development [inference]

regulation of nurse cell apoptotic process

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction

regulation of neuromuscular junction development [inference]

regulation of synaptic assembly at neuromuscular junction

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction

regulation of reproductive process [inference]

regulation of nurse cell apoptotic process

regulation of biological quality [inference]

regulation of female receptivity

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane	IBA ISM	28878041
presynapse
vesicle	IDA	21562262
late endosome membrane	IDA	12408844
lysosomal membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

late endosome membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane [inference]

late endosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle

presynapse

Displaying 1 entry
GO Term	Evidence Code	PMID
transmembrane transporter activity	IBA IEA ISM	28878041

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transporter

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
MFS transporter superfamily
Major facilitator superfamily domain
Major facilitator superfamily

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
membrane	FB:FBrf0231198
vesicle	PMID:21562262
late endosome membrane	PMID:12408844

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0111643	autosomal recessive nonsyndromic deafness 115	Alliance of Genome Resources
DOID:14503	neuronal ceroid lipofuscinosis	Alliance of Genome Resources
DOID:1927	sphingolipidosis	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 56 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Rattus norvegicus	497946		RGD:1561884
Danio rerio	568117		ZFIN:ZDB-GENE-030131-5843
Danio rerio	568387		ZFIN:ZDB-GENE-060531-7
Danio rerio	799873		ZFIN:ZDB-GENE-020228-1
Drosophila pseudoobscura	4805638	7237_1:0015ef
Drosophila ananassae	6494159	7217_1:001bea
Drosophila yakuba	6531475	7245_1:00188d
Drosophila erecta	6548851	7220_1:002aa7
Drosophila grimshawi	6560787	7222_1:000a80
Drosophila mojavensis	6579401	7230_1:002ad0

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements