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4-aminobutyrate aminotransferase

Summary

Gene Symbol

ABAT

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 453903
KEGG Gene ID: ptr:453903
PubChem: 453903

Annotation

Keyword

Aminotransferase
Methyltransferase
Neurotransmitter degradation
Pyridoxal phosphate
Reference proteome
S-adenosyl-L-methionine

Proteins

Displaying **all 3** entries
UniProt	Protein Name
H2RAD8
A0A2I3T3Z8	(S)-3-amino-2-methylpropionate transaminase GABA aminotransferase Gamma-amino-N-butyrate transaminase L-AIBAT
A0A6D2XD93	(S)-3-amino-2-methylpropionate transaminase GABA aminotransferase Gamma-amino-N-butyrate transaminase L-AIBAT

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein methylation	IEA	30032202
gamma-aminobutyric acid catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid catabolic process

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

methylation [inference]

macromolecule methylation [inference]

protein methylation

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid catabolic process

monocarboxylic acid metabolic process [inference]

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid catabolic process

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid catabolic process

monocarboxylic acid metabolic process [inference]

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid catabolic process

monocarboxylic acid metabolic process [inference]

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation

macromolecule modification [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation

macromolecule methylation [inference]

protein methylation

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid catabolic process

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid catabolic process

monocarboxylic acid metabolic process [inference]

gamma-aminobutyric acid metabolic process [inference]

gamma-aminobutyric acid catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

gamma-aminobutyric acid catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
nucleus	IEA	30032202
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
4-aminobutyrate transaminase activity	IEA	22301074 30032202
pyridoxal phosphate binding	IEA	22301074 30032202
protein methyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

protein methyltransferase activity

transferase activity, transferring nitrogenous groups [inference]

transaminase activity [inference]

4-aminobutyrate transaminase activity

catalytic activity, acting on a protein [inference]

protein methyltransferase activity

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

heterocyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

pyridoxal phosphate binding

organic cyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K13524

Name

4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22]

References

10989446

Rhea

RHEA:23352

2-oxoglutarate + 4-aminobutanoate

L-glutamate + succinate semialdehyde

Enzyme

2.6.1.19

PMID

RHEA:13993

2-oxoglutarate + (S)-3-amino-2-methylpropanoate

L-glutamate + 2-methyl-3-oxopropanoate

Enzyme

2.6.1.22

PMID

Ortholog

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Species	Gene ID	Orthologous MAtrix
Pongo abelii	100174312	PONAB10173
Pongo abelii	100434836	PONAB10156
Homo sapiens	18	HUMAN26515
Homo sapiens	79091	HUMAN26506
Canis lupus familiaris	479856	CANLF16587
Canis lupus familiaris	610231	CANLF16588
Vulpes vulpes	112923301	VULVU16703
Ursus americanus	123783550	URSAM03151
Ailuropoda melanoleuca	100470601	AILME12319
Mustela putorius furo	101676585	MUSPF14278