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ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3

Summary

Gene Symbol

ST8SIA3

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 455436
KEGG Gene ID: ptr:455436
PubChem: 455436

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P61644	Alpha-2,8-sialyltransferase 8C Alpha-2,8-sialyltransferase III Ganglioside GD3 synthase ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 Sia-a2,3-Gal-b1,4-Glc-NAc-R:a2,8-sialyltransferase Sialyltransferase 8C Sialyltransferase St8Sia III

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
N-glycan processing	IEA	30032202
oligosaccharide metabolic process	IEA	30032202
sialylation
protein glycosylation	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

sialylation

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

Displaying 1 entry
GO Term	Evidence Code	PMID
Golgi membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity	IEA	30032202
sialyltransferase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity

alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K06613

Name

alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8C) [EC:2.4.3.-]

References

9826427

Rhea

RHEA:19313

an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl derivative + CMP-N-acetyl-β-neuraminate

an N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl derivative + H⁺ + CMP

Enzyme

2.4.3.8

PMID

Ortholog

Displaying entries **1 - 10** of 63 in total

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Species	Gene ID	Orthologous MAtrix
Latimeria chalumnae	102353792	LATCH14473
Danio rerio	553510	DANRE20472
Astyanax mexicanus	103028989	ASTMX07765
Ictalurus punctatus	108278431	ICTPU11265
Electrophorus electricus	113586281	ELEEL37135
Salmo salar	106568531	SALSA28091
Salmo salar	106572171	SALSA67797
Salmo trutta	115149563	SALTR20179
Salmo trutta	115160152	SALTR69889
Oreochromis niloticus	100701071	ORENI67538

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements