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angiotensin II receptor type 1

Summary

Gene Symbol

AGTR1

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 460762
PubChem: 460762

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A663DIA4
Q9GLN9	Angiotensin II type-1 receptor
K7BAD0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
regulation of vasoconstriction	IEA	22301074
maintenance of blood vessel diameter homeostasis by renin-angiotensin
brain development	IEA	30032202
calcium-mediated signaling	IEA	30032202
cell chemotaxis	IEA	30032202

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

cell motility [inference]

cell migration [inference]

cell chemotaxis

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

renal system process [inference]

renal system process involved in regulation of systemic arterial blood pressure [inference]

renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure [inference]

maintenance of blood vessel diameter homeostasis by renin-angiotensin

endocrine process [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin [inference]

maintenance of blood vessel diameter homeostasis by renin-angiotensin

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

brain development

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of vasoconstriction

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

regulation of blood pressure [inference]

regulation of systemic arterial blood pressure [inference]

regulation of systemic arterial blood pressure mediated by a chemical signal [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin [inference]

maintenance of blood vessel diameter homeostasis by renin-angiotensin

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IEA	30032202
membrane	IEA	22301074
plasma membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
angiotensin type I receptor activity
C-C chemokine receptor activity	IEA	30032202
angiotensin type II receptor activity	IEA	22301074
C-C chemokine binding	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytokine binding [inference]

chemokine binding [inference]

C-C chemokine binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

angiotensin receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity [inference]

C-C chemokine receptor activity

G protein-coupled receptor activity [inference]

G protein-coupled chemoattractant receptor activity [inference]

chemokine receptor activity [inference]

C-C chemokine receptor activity

G protein-coupled peptide receptor activity [inference]

angiotensin receptor activity [inference]

immune receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity [inference]

C-C chemokine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level: Hominidae
Group Name: Angiotensin II receptor type 1

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Gene Ontology
phospholipase C-activating angiotensin-activated signaling pathway
positive regulation of cytosolic calcium ion concentration
regulation of vasoconstriction

Displaying **all 4** entries
InterPro
Angiotensin II receptor family
Angiotensin II receptor type 1
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **21 - 30** of **111** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Ailuropoda melanoleuca	100471220		AILME04727
Sus scrofa	100519976		PIGXX04895
Anolis carolinensis	100555655		ANOCA04057
Nomascus leucogenys	100603931		NOMLE03850
Oreochromis niloticus	100702961		ORENI74787
Cricetulus griseus	100750798		CRIGR18640
Cricetulus griseus	100755233		CRIGR02493
Sarcophilus harrisii	100927259		SARHA18414
Otolemur garnettii	100954924		OTOGA12416
Pan paniscus	100992718	9597_0:001062	PANPA29011