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angiotensin II receptor type 1

Summary

Gene Symbol

AGTR1

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 460762
PubChem: 460762

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A663DIA4
Q9GLN9	Angiotensin II type-1 receptor
K7BAD0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
regulation of vasoconstriction	IEA	22301074
maintenance of blood vessel diameter homeostasis by renin-angiotensin
brain development	IEA	30032202
calcium-mediated signaling	IEA	30032202
cell chemotaxis	IEA	30032202

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

cell motility [inference]

cell migration [inference]

cell chemotaxis

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

renal system process [inference]

renal system process involved in regulation of systemic arterial blood pressure [inference]

renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure [inference]

maintenance of blood vessel diameter homeostasis by renin-angiotensin

endocrine process [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin [inference]

maintenance of blood vessel diameter homeostasis by renin-angiotensin

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

brain development

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of vasoconstriction

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

regulation of blood pressure [inference]

regulation of systemic arterial blood pressure [inference]

regulation of systemic arterial blood pressure mediated by a chemical signal [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin [inference]

maintenance of blood vessel diameter homeostasis by renin-angiotensin

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IEA	30032202
membrane	IEA	22301074
plasma membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
angiotensin type I receptor activity
C-C chemokine receptor activity	IEA	30032202
angiotensin type II receptor activity	IEA	22301074
C-C chemokine binding	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytokine binding [inference]

chemokine binding [inference]

C-C chemokine binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

angiotensin receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity [inference]

C-C chemokine receptor activity

G protein-coupled receptor activity [inference]

G protein-coupled chemoattractant receptor activity [inference]

chemokine receptor activity [inference]

C-C chemokine receptor activity

G protein-coupled peptide receptor activity [inference]

angiotensin receptor activity [inference]

immune receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity [inference]

C-C chemokine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level: Hominidae
Group Name: Angiotensin II receptor type 1

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Gene Ontology
phospholipase C-activating angiotensin-activated signaling pathway
positive regulation of cytosolic calcium ion concentration
regulation of vasoconstriction

Displaying **all 4** entries
InterPro
Angiotensin II receptor family
Angiotensin II receptor type 1
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **31 - 40** of **111** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Papio anubis	101003219		PAPAN26302
Saimiri boliviensis boliviensis	101037991		SAIBB08648
Takifugu rubripes	101065754		TAKRU01788
Felis catus	101082936		FELCA22048
Gorilla gorilla gorilla	101128433	9595_0:001388	GORGO28507
Octodon degus	101566521		OCTDE06086
Jaculus jaculus	101596637		JACJA15266
Jaculus jaculus	101604353		JACJA07252
Mustela putorius furo	101685981		MUSPF12611
Ficedula albicollis	101812375		FICAL01463