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Wnt family member 2

Summary

Gene Symbol

WNT2

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 463673
PubChem: 463673

Annotation

Keyword

Developmental protein
Disulfide bond
Extracellular matrix
Glycoprotein
Lipoprotein
Reference proteome
Signal
Wnt signaling pathway

Proteins

Displaying **all 3** entries
UniProt	Protein Name
K7B9K0
Q2QLE7
A0A663DHQ6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
multicellular organism development	IEA	22301074 30032202
neuron differentiation	IEA	30032202
cell fate commitment	IEA	30032202
canonical Wnt signaling pathway	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway [inference]

canonical Wnt signaling pathway

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

cell fate commitment

multicellular organismal process [inference]

multicellular organism development

developmental process [inference]

anatomical structure development [inference]

multicellular organism development

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

cell fate commitment

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway [inference]

canonical Wnt signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IEA	22301074 30032202
extracellular space	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
frizzled binding	IEA	30032202
cytokine activity	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

frizzled binding

receptor ligand activity [inference]

cytokine activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Wnt

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
canonical Wnt signaling pathway
cell fate commitment
cytokine activity
neuron differentiation
signaling receptor binding

Displaying **all 3** entries
InterPro
Wnt protein, conserved site
Wnt, C-terminal domain
Wnt

Ortholog

Displaying entries **1 - 10** of 65 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	7472	HUMAN90985
Mus musculus	22413	MOUSE49034
Rattus norvegicus	114487	RATNO30241
Felis catus	493672	FELCA05642
Bos taurus	493729	BOVIN27990
Macaca mulatta	704991	MACMU32443
Monodelphis domestica	100011991	MONDO35595
Equus caballus	100056092	HORSE31991
Ornithorhynchus anatinus	100077640	ORNAN01699
Oryctolagus cuniculus	100126569	RABIT11493