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myosin IA

Summary

Gene Symbol

MYO1A

Organism

Homo sapiens (human)

External Links

NCBI Gene

4640

PubChem

4640

Alliance of Genome Resources

HGNC:7595

Annotation

Keyword

ATP-binding
Actin-binding
Calmodulin-binding
Myosin
Phosphoprotein
Reference proteome
Repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9UBC5	Brush border myosin I Myosin I heavy chain
B2R643	Brush border myosin I Myosin I heavy chain

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
sensory perception of sound	IBA IMP	12736868
endocytosis	IBA
vesicle localization	IMP	8692943
microvillus assembly	IEA
actin filament-based movement	IBA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis

actin filament-based process [inference]

actin filament-based movement

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

microvillus assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

microvillus assembly

plasma membrane bounded cell projection organization [inference]

microvillus organization [inference]

microvillus assembly

plasma membrane bounded cell projection assembly [inference]

microvillus assembly

supramolecular fiber organization [inference]

actin filament organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis

import into cell [inference]

endocytosis

organelle localization [inference]

vesicle localization

Displaying entries **6 - 10** of 12 in total

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GO Term	Evidence Code	PMID
cortical actin cytoskeleton	IDA	8692943
filamentous actin	IDA	9858156
plasma membrane	IBA
brush border	IBA IDA	9858156
actin cytoskeleton	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft

lateral plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

microvillus

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

cortical cytoskeleton [inference]

cortical actin cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

cortical cytoskeleton [inference]

cortical actin cytoskeleton

cluster of actin-based cell projections [inference]

brush border

Displaying **all 4** entries
GO Term	Evidence Code	PMID
microfilament motor activity	IBA
actin filament binding	IBA
calmodulin binding	IEA
ATP binding	IEA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microfilament motor activity

binding [inference]

protein binding [inference]

calmodulin binding

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein-containing complex binding [inference]

actin filament binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microfilament motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

myosin

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 5** entries
Gene Ontology
ATP binding
actin binding
actin filament binding
cytoskeletal motor activity
nucleotide binding

Displaying **all 3** entries
InterPro
Kinesin motor domain superfamily
Myosin head, motor domain
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10003	sensorineural hearing loss	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of 62 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Chrysemys picta bellii	101943525			CHRPI25326
Ictidomys tridecemlineatus	101966463			ICTTR16728
Chinchilla lanigera	102019146			CHILA14909
Macaca fascicularis	102116998			MACFA03472
Capra hircus	102181929			CAPHI24817
Myotis lucifugus	102421089			MYOLU08038
Ornithorhynchus anatinus	103168872			ORNAN01925
Chlorocebus sabaeus	103238549			CHLSB02347
Carlito syrichta	103267654			CARSF18700
Nannospalax galili	103742931			NANGA23306

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024