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Guidelines

MIRAGE

myosin VIIB

Summary

Gene Symbol

MYO7B

Organism

Homo sapiens (human)

External Links

NCBI Gene

4648

PubChem

4648

Alliance of Genome Resources

HGNC:7607

Annotation

Keyword

3D-structure
ATP-binding
Actin-binding
Alternative splicing
Cell projection
Cytoskeleton
Differentiation
Myosin
Phosphoprotein
Reference proteome
Repeat
SH3 domain

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6PIF6

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
endocytosis	IBA
actin filament organization	IBA
sensory organ development	IBA
sensory perception of sound	IBA
actin filament-based movement	IBA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis

actin filament-based process [inference]

actin filament-based movement

cellular developmental process [inference]

cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

brush border assembly

supramolecular fiber organization [inference]

actin filament organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

sensory organ development

cellular developmental process [inference]

cell differentiation

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis

import into cell [inference]

endocytosis

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
microvillus	IDA	24725409 32209652
microvillus	IBA
brush border	IDA	24725409
actin cytoskeleton	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

myosin complex

cellular anatomical entity [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

microvillus

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

apical cytoplasm

cluster of actin-based cell projections [inference]

brush border

Displaying **all 4** entries
GO Term	Evidence Code	PMID
microfilament motor activity	IBA
protein binding	IPI	24725409 26812018 32209652
ATP binding	IEA
actin filament binding	IBA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microfilament motor activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein-containing complex binding [inference]

actin filament binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microfilament motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

myosin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
ATP binding
actin binding
cytoskeletal motor activity
nucleotide binding

Displaying entries **1 - 10** of 15 in total

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InterPro
Band 4.1 domain
Class VII myosin, motor domain
FERM central domain
FERM domain
FERM superfamily, second domain
FERM/acyl-CoA-binding protein superfamily
IQ motif, EF-hand binding site
Kinesin motor domain superfamily
MyTH4 domain superfamily
MyTH4 domain

Ortholog

Displaying entries **21 - 30** of 53 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Otolemur garnettii	100955081		OTOGA03147
Pan paniscus	100971650		PANPA25651
Papio anubis	101009814		PAPAN01817
Saimiri boliviensis boliviensis	101037274		SAIBB19283
Felis catus	101095671		FELCA18872
Ovis aries	101118339		SHEEP09310
Octodon degus	101574313		OCTDE03732
Jaculus jaculus	101597244		JACJA19979
Mustela putorius furo	101675830		MUSPF01678
Ficedula albicollis	101811393		FICAL10990

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Last updated: December 8, 2025