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fructose-bisphosphatase 1

Summary

Gene Symbol

FBP1

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 465260
KEGG Gene ID: ptr:465260
PubChem: 465260

Annotation

Keyword

Acetylation
Allosteric enzyme
Carbohydrate metabolism
Gluconeogenesis
Hydrolase
Magnesium
Metal-binding
Phosphoprotein
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2J8JHD6	D-fructose-1,6-bisphosphate 1-phosphohydrolase 1 Liver FBPase
A0A6D2XM47	D-fructose-1,6-bisphosphate 1-phosphohydrolase 1 Liver FBPase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
sucrose biosynthetic process	IEA	30032202
fructose metabolic process	IEA	30032202
fructose 6-phosphate metabolic process	IEA	30032202
gluconeogenesis	IEA	30032202
fructose 1,6-bisphosphate metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

organophosphate metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

oligosaccharide metabolic process [inference]

disaccharide metabolic process [inference]

sucrose metabolic process [inference]

sucrose biosynthetic process

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

oligosaccharide metabolic process [inference]

disaccharide metabolic process [inference]

sucrose metabolic process [inference]

sucrose biosynthetic process

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organophosphate metabolic process [inference]

carbohydrate derivative metabolic process [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

sucrose biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

organophosphate metabolic process [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytoplasm	IEA	30032202
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying 1 entry
GO Term	Evidence Code	PMID
fructose 1,6-bisphosphate 1-phosphatase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

carbohydrate phosphatase activity [inference]

sugar-phosphatase activity [inference]

fructose 1,6-bisphosphate 1-phosphatase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

fructose-1 6-bisphosphatase

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
fructose 1,6-bisphosphate 1-phosphatase activity
fructose 1,6-bisphosphate metabolic process
fructose 6-phosphate metabolic process
fructose metabolic process
gluconeogenesis
hydrolase activity
metal ion binding
phosphoric ester hydrolase activity
sucrose biosynthetic process

Displaying **all 5** entries
InterPro
Fructose-1,6-bisphosphatase class 1
Fructose-1,6-bisphosphatase, active site
Fructose-1,6-bisphosphatase
Fructose-1-6-bisphosphatase class 1, C-terminal
Fructose-1-6-bisphosphatase class I, N-terminal

KEGG BRITE Database

Orthology

K03841

Name

fructose-1,6-bisphosphatase I [EC:3.1.3.11]

References

7589895

Rhea

RHEA:11064

H₂O + β-D-fructose 1,6-bisphosphate

phosphate + β-D-fructose 6-phosphate

Enzyme

3.1.3.11

PMID

Ortholog

Displaying entries **1 - 10** of 79 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	2203	HUMAN97656
Mus musculus	14121	MOUSE12211
Rattus norvegicus	24362	RATNO12434
Danio rerio	282672	DANRE36953
Danio rerio	335231	DANRE36255
Sus scrofa	397038	PIGXX00380
Canis lupus familiaris	476299	CANLF00377
Bos taurus	513483	BOVIN34905
Oryctolagus cuniculus	100008863	RABIT00406
Monodelphis domestica	100013279	MONDO28643

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Acknowledgements