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Standards Ontologies Notations
CEA cell adhesion molecule 6

Summary
Gene Symbol
  • CEACAM6
Aliases
  • CD66c
Organism
Homo sapiens (human)
External Links
NCBI Gene
4680
HGNC
1818
KEGG Gene ID
hsa:4680
PubChem
4680
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Apoptosis
  • Cell adhesion
  • Cell membrane
  • Direct protein sequencing
  • Disulfide bond
  • GPI-anchor
  • Immunoglobulin domain
  • Oncogene
  • Reference proteome
  • Repeat
  • Signal
Proteins
Displaying 1 entry
UniProt Protein Name
P40199
  • Non-specific crossreacting antigen
  • Normal cross-reacting antigen
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 9 in total
GO Term Evidence Code PMID
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
positive regulation of heterotypic cell-cell adhesion
positive regulation of cell migration
homophilic cell adhesion via plasma membrane adhesion molecules
positive regulation of endothelial cell-matrix adhesion via fibronectin
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
Human Protein Atlas
ENSG00000086548

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas
KEGG BRITE Database
Orthology
K06499
Name
carcinoembryonic antigen-related cell adhesion molecule
References
Disease
Disease Ontology
Displaying entries 1 - 10 of 108 in total
DO ID Disease Name Source
DOID:0050214 Lambert-Eaton myasthenic syndrome
DOID:0050387 nonpapillary renal cell carcinoma
DOID:0050589 inflammatory bowel disease
DOID:0050657 Bannayan-Riley-Ruvalcaba syndrome
DOID:0050865 tongue squamous cell carcinoma
DOID:0060180 colitis
DOID:0060185 Clostridium difficile colitis
DOID:0060189 ileitis
DOID:0060190 ileocolitis
DOID:0060192 Crohn's colitis
The Human Phenotype Ontology
Displaying entries 11 - 20 of 32 in total
HPO ID HPO Term
HP:0001738 Exocrine pancreatic insufficiency
HP:0002020 Gastroesophageal reflux
HP:0002024 Malabsorption
HP:0002035 Rectal prolapse
HP:0002099 Asthma
HP:0002105 Hemoptysis
HP:0002107 Pneumothorax
HP:0002110 Bronchiectasis
HP:0002205 Recurrent respiratory infections
HP:0002570 Steatorrhea
Displaying 1 entry
Disease ID Disease Name
ORPHA:586
  • cystic fibrosis
Ortholog
Displaying entries 1 - 10 of 15 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
557409 ZFIN:ZDB-GENE-080226-6
799170 ZFIN:ZDB-GENE-100921-41
100329252 ZFIN:ZDB-GENE-100921-33
100145081 Xenbase:XB-GENE-5920801
101730286 Xenbase:XB-GENE-22169429
705689 MACMU19070
707824 MACMU19070
106994775 MACMU19070
109024100 GORGO16248
100614697 PANTR18390
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024