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NEDD4 E3 ubiquitin protein ligase

Summary

Gene Symbol

NEDD4

Organism

Homo sapiens (human)

External Links

NCBI Gene

4734

KEGG Gene ID

PubChem

4734

Alliance of Genome Resources

HGNC:7727

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cell membrane
Cytoplasm
Host-virus interaction
Isopeptide bond
Neurogenesis
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Transferase
Ubl conjugation
Ubl conjugation pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
P46934	Cell proliferation-inducing gene 53 protein HECT-type E3 ubiquitin transferase NEDD4 Neural precursor cell expressed developmentally down-regulated protein 4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 51 in total

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GO Term	Evidence Code	PMID
negative regulation of transcription by RNA polymerase II	IMP
adaptive immune response
outflow tract morphogenesis
endocardial cushion development
ubiquitin-dependent protein catabolic process	IDA

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

adaptive immune response

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

signal transduction [inference]

hormone-mediated signaling pathway [inference]

steroid hormone receptor signaling pathway [inference]

nuclear receptor-mediated steroid hormone signaling pathway [inference]

nuclear receptor-mediated corticosteroid signaling pathway [inference]

nuclear receptor-mediated glucocorticoid signaling pathway

progesterone receptor signaling pathway

intracellular signal transduction [inference]

intracellular receptor signaling pathway [inference]

nuclear receptor-mediated signaling pathway [inference]

nuclear receptor-mediated steroid hormone signaling pathway [inference]

nuclear receptor-mediated corticosteroid signaling pathway [inference]

nuclear receptor-mediated glucocorticoid signaling pathway

progesterone receptor signaling pathway

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

receptor catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

receptor catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein metabolic process [inference]

protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K63-linked ubiquitination

protein monoubiquitination

receptor metabolic process [inference]

receptor catabolic process

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K63-linked ubiquitination

protein monoubiquitination

primary metabolic process [inference]

protein metabolic process [inference]

protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K63-linked ubiquitination

protein monoubiquitination

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport

protein targeting to lysosome

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development

cell junction organization [inference]

synapse organization [inference]

neuromuscular junction development

viral process [inference]

viral budding

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

developmental process [inference]

anatomical structure morphogenesis [inference]

outflow tract morphogenesis

tube morphogenesis [inference]

blood vessel morphogenesis

anatomical structure development [inference]

animal gross anatomical part developmental process [inference]

tissue development [inference]

mesenchyme development [inference]

endocardial cushion development

biological process involved in interspecies interaction between organisms [inference]

formation of structure involved in a symbiotic process

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

immune response [inference]

adaptive immune response

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to UV [inference]

cellular response to UV

cellular response to light stimulus [inference]

cellular response to UV

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

response to chemical [inference]

response to metal ion [inference]

response to calcium ion

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to organelle [inference]

protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to lysosome [inference]

protein targeting to lysosome

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

protein transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport

protein targeting to lysosome

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport

protein targeting to lysosome

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport

protein targeting to lysosome

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of potassium ion export across plasma membrane [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

negative regulation of sodium ion transport

regulation of potassium ion transport [inference]

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of potassium ion export across plasma membrane [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of potassium ion export across plasma membrane [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of monoatomic ion transport [inference]

negative regulation of sodium ion transport

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of monoatomic ion transport [inference]

negative regulation of sodium ion transport

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of monoatomic ion transport [inference]

negative regulation of sodium ion transport

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of dendrite morphogenesis

regulation of dendrite development [inference]

regulation of dendrite morphogenesis

regulation of cellular process [inference]

signal transduction [inference]

hormone-mediated signaling pathway [inference]

steroid hormone receptor signaling pathway [inference]

nuclear receptor-mediated steroid hormone signaling pathway [inference]

nuclear receptor-mediated corticosteroid signaling pathway [inference]

nuclear receptor-mediated glucocorticoid signaling pathway

progesterone receptor signaling pathway

intracellular signal transduction [inference]

intracellular receptor signaling pathway [inference]

nuclear receptor-mediated signaling pathway [inference]

nuclear receptor-mediated steroid hormone signaling pathway [inference]

nuclear receptor-mediated corticosteroid signaling pathway [inference]

nuclear receptor-mediated glucocorticoid signaling pathway

progesterone receptor signaling pathway

regulation of cell communication

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

regulation of autophagy [inference]

regulation of macroautophagy

regulation of protein catabolic process

positive regulation of protein catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein catabolic process

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein catabolic process

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of potassium ion export across plasma membrane [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion export across plasma membrane

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of dendrite development [inference]

regulation of dendrite morphogenesis

regulation of synapse organization

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport

regulation of biological quality [inference]

regulation of membrane potential

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GO Term	Evidence Code	PMID
ubiquitin ligase complex	ISS
ubiquitin ligase complex	IEA
chromatin	IDA
nucleus	IDA
nucleus	IPI

GO Hierarchy

cellular component

protein-containing complex

intracellular protein-containing complex [inference]

ubiquitin ligase complex

catalytic complex [inference]

transferase complex [inference]

ubiquitin ligase complex

cellular anatomical structure [inference]

cytoplasm

cell cortex

cytosol

postsynaptic cytosol

membrane

plasma membrane

plasma membrane region [inference]

apicolateral plasma membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
ubiquitin-protein transferase activity	IDA
ubiquitin-protein transferase activity	IMP
ubiquitin-protein transferase activity	IEA
protein binding	IPI
channel inhibitor activity	IDA