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MIRAGE
protein C, inactivator of coagulation factors Va and VIIIa
Summary
- Gene Symbol
-
- PROC
- Organism
- Canis lupus familiaris (dog)
Annotation
- Keyword
-
- Blood coagulation
- Calcium
- Cleavage on pair of basic residues
- Disulfide bond
- EGF-like domain
- Endoplasmic reticulum
- Gamma-carboxyglutamic acid
- Glycoprotein
- Golgi apparatus
- Hydroxylation
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q28278 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| blood coagulation | ||
| negative regulation of blood coagulation |
|
|
| negative regulation of apoptotic process |
|
|
| negative regulation of inflammatory response |
|
GO Hierarchy
biological process
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| endoplasmic reticulum |
|
|
| Golgi apparatus |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type endopeptidase activity | ||
| calcium ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- serine protease
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| hydrolase activity |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 5624 | HUMAN64633 | ||
| 19123 | MOUSE23485 | ||
| 25268 | RATNO13720 | ||
| 281428 | BOVIN23858 | ||
| 393327 | DANRE28803 | ||
| 396954 | PIGXX08919 | ||
| 459593 | PANTR28606 | ||
| 699077 | MACMU05799 | ||
| 100009223 | RABIT11583 | ||
| 100026692 | MONDO24377 |
