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ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

Summary

Gene Symbol

ST8SIA1

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene: 477672
KEGG Gene ID: cfa:477672
PubChem: 477672

Annotation

Keyword

Disulfide bond
Glycoprotein
Golgi apparatus
Reference proteome
Signal-anchor
Sphingolipid metabolism
Transferase
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8C0TU42	Alpha-2,8-sialyltransferase 8A Ganglioside GD3 synthase Sialyltransferase 8A Sialyltransferase St8Sia I
A0A8I3S0P4	Alpha-2,8-sialyltransferase 8A Ganglioside GD3 synthase Sialyltransferase 8A Sialyltransferase St8Sia I

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
N-glycan processing	IEA	30032202
oligosaccharide metabolic process	IEA	30032202
protein glycosylation	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing

protein modification process [inference]

protein glycosylation

Displaying 1 entry
GO Term	Evidence Code	PMID
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity [inference]

alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K03371

Name

alpha-N-acetylneuraminate alpha-2,8-sialyltransferase (sialyltransferase 8A) [EC:2.4.3.8]

References

8058740

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R13175	2.4.3.8	G32254QI	G50116PC
R05940	2.4.3.8	G91237TK	G98544DH
R05947	2.4.3.8	G98544DH	G93899SO
R06032	2.4.3.8	G01767JJ	G70647TI

Rhea

RHEA:19313

an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl derivative + CMP-N-acetyl-β-neuraminate

an N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl derivative + H⁺ + CMP

Enzyme

2.4.3.8

PMID

Ortholog

Displaying entries **1 - 10** of 75 in total

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Species	Gene ID	Orthologous MAtrix
Callorhinchus milii	103181078	CALMI21900
Danio rerio	553210	DANRE33846
Astyanax mexicanus	103035159	ASTMX02003
Ictalurus punctatus	108279455	ICTPU12464
Ictalurus punctatus	108279490	ICTPU13124
Electrophorus electricus	113584008	ELEEL31963
Salmo salar	106609639	SALSA52694
Salmo trutta	115180086	SALTR54997
Salmo trutta	115199122	SALTR65770
Gadus morhua	115532215	GADMO24562

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements