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MIRAGE
ST6 beta-galactoside alpha-2,6-sialyltransferase 1

Summary
Gene Symbol
  • ST6GAL1
Organism
Canis lupus familiaris (dog)
NCBI Gene
478668
KEGG Gene ID
cfa:478668
PubChem
478668
Annotation
Keyword
  • Glycoprotein
  • Golgi apparatus
  • Reference proteome
  • Signal-anchor
  • Transferase
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
A0A8I3S5C7
A0A8C0T0L0
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
beta-galactoside alpha-2,6-sialyltransferase
Functional Category
  • H: Coenzyme transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying all 4 entries
Gene Ontology
beta-galactoside alpha-2,6-sialyltransferase activity
sialylation
sialyltransferase activity
transferase activity
Displaying all 2 entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29
KEGG BRITE Database
Orthology
K00778
Name
beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1) [EC:2.4.3.1]
References
Reactions
Displaying 1 entry
KEGG Reaction Enzyme Acceptor Product
R05990
Rhea

RHEA:21552

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate
H+ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP
Enzyme
PMID

RHEA:52104

a β-D-galactoside + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl derivative + H+ + CMP
Enzyme
PMID

RHEA:11836

N-acetyl-β-lactosamine + CMP-N-acetyl-β-neuraminate
H+ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosamine + CMP
Enzyme
PMID
Ortholog
Displaying entries 21 - 30 of 76 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
100861310 CAPHI12124
100913159 SHEEP01534
100922140 SARHA06614
100958396 OTOGA09623
100969795 PANPA29473
101015073 PAPAN24832
101032294 SAIBB11865
101097832 FELCA22567
101142727 GORGO27661
101319987 TURTR12983
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025